Literature DB >> 426840

Inhibition of sterol synthesis in animal cells by 15-oxygenated sterols with the unnatural cis-C-D ring junction-"5alpha,14beta-cholest-7-en-15alpha-ol-3-one and 5alpha,14beta-cholest-7-en-15beta-ol-3-one.

G J Schroepfer, R A Pascal, A A Kandutsch.   

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Year:  1979        PMID: 426840     DOI: 10.1016/0006-2952(79)90511-2

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN: 0006-2952            Impact factor:   5.858


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  2 in total

1.  5 alpha-Cholest-8(14)-en-3 beta-ol-15-one, a potent inhibitor of sterol biosynthesis, lowers serum cholesterol and alters distributions of cholesterol in lipoproteins in baboons.

Authors:  G J Schroepfer; E J Parish; A Kisic; E M Jackson; C M Farley; G E Mott
Journal:  Proc Natl Acad Sci U S A       Date:  1982-05       Impact factor: 11.205

2.  Inhibition of sterol biosynthesis by 14 alpha-hydroxy-delta 7-sterols.

Authors:  G J Schroepfer; R A Pascal; A A Kandutsch
Journal:  Experientia       Date:  1980-05-15
  2 in total

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