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Literature DB >> 426500

Autoradiographic localization of [3H]gentamicin in the proximal renal tubules of mice.

Abstract

The site of localization of [(3)H]gentamicin within mouse kidney is shown to be the proximal renal tubule by coincidence of the radioactivity, as visualized by autoradiography, and the mucopolysaccharide-rich microvilli characteristic of proximal convoluted tubules, as visualized by histochemical staining.

Entities: Chemical Species

Mesh：

Substances：
Gentamicins

Year: 1979 PMID： 426500 PMCID： PMC352612 DOI： 10.1128/AAC.15.1.131

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

12 in total

1. Experimental aminoglycoside nephrotoxicity.

Authors: F C Luft; V Patel; M N Yum; B Patel; S A Kleit
Journal: J Lab Clin Med Date: 1975-08

2. The renal handling of polybasic drugs. 1. Gentamicin and aprotinin in intact animals.

Authors: M Just; G Erdmann; E Habermann
Journal: Naunyn Schmiedebergs Arch Pharmacol Date: 1977-10 Impact factor: 3.000

3. Concentrations of gentamicin and amikacin in human kidneys.

Authors: C Q Edwards; C R Smith; K L Baughman; J F Rogers; P S Lietman
Journal: Antimicrob Agents Chemother Date: 1976-06 Impact factor: 5.191

4. Renal parenchymal accumulation of aminoglycoside antibiotics in rats.

Authors: F C Luft; S A Kleit
Journal: J Infect Dis Date: 1974-12 Impact factor: 5.226

5. Nephrotoxicity of gentamicin.

Authors: J C Kosek; R I Mazze; M J Cousins
Journal: Lab Invest Date: 1974-01 Impact factor: 5.662

6. [Gentamicin concentrations in tissues and body fluids of various animals].

Authors: H Wahlig; A Metallinos; W Hameister; R Bergmann
Journal: Int J Clin Pharmacol Date: 1974-10

7. A light and electron microscopic analysis of gentamicin nephrotoxicity in rats.

Authors: D C Houghton; M Hartnett; M Campbell-Boswell; G Porter; W Bennett
Journal: Am J Pathol Date: 1976-03 Impact factor: 4.307

8. Persistence of sisomicin and gentamicin in renal cortex and medulla compared with other organs and serum of rats.

Authors: J Fabre; M Rudhardt; P Blanchard; C Regamey
Journal: Kidney Int Date: 1976-12 Impact factor: 10.612

9. Renal damage caused by gentamicin: a study of the effects on renal morphology and urinary enzyme excretion.

Authors: J M Wellwood; D Lovell; A E Thompson; J R Tighe
Journal: J Pathol Date: 1976-03 Impact factor: 7.996

10. Gentamicin nephrotoxicity. II. Physiological, biochemical and morphological effects of prolonged administration to rats.

Authors: F E Cuppage; K Setter; P Sullivan; E J Reitzes; A O Melnykovych
Journal: Virchows Arch B Cell Pathol Date: 1977-06-24

7 in total

1. An immunohistochemical method for the study of aminoglycoside ototoxicity in the guinea pig cochlea using decalcified frozen sections.

Authors: T Hayashida
Journal: Arch Otorhinolaryngol Date: 1989

2. Autoradiographic study of tobramycin uptake by proximal and distal tubules of normal and pyelonephritic rats.

Authors: M G Bergeron; Y Marois; C Kuehn; F J Silverblatt
Journal: Antimicrob Agents Chemother Date: 1987-09 Impact factor: 5.191

Review 3. Commonly used antibacterial and antifungal agents for hospitalised paediatric patients: implications for therapy with an emphasis on clinical pharmacokinetics.

Authors: J Singh; B Burr; D Stringham; A Arrieta
Journal: Paediatr Drugs Date: 2001 Impact factor: 3.022