Literature DB >> 4209271

Thyrotropin-releasing hormone: regional distribution in rat brain.

A Winokur, R D Utiger.   

Abstract

A sensitive and specific radioimmnunoassay has been used to measure the distribution of thyrotropin-releasing hormone (TRH) in rat brain. All areas of brain tested, except cerebellum, contained readily measurable amounts of TRH. The hypothalamus contained only 31.2 percent of the total brain content of TRH. These results support recent suggestions of central actions for TRH in addition to its hypophysiotropic functions.

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Year:  1974        PMID： 4209271     DOI： 10.1126/science.185.4147.265

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  41 in total

1.  The synthetic TRH analogue taltirelin exerts modality-specific antinociceptive effects via distinct descending monoaminergic systems.

Authors:  M Tanabe; Y Tokuda; K Takasu; K Ono; M Honda; H Ono
Journal:  Br J Pharmacol       Date:  2007-01-15       Impact factor: 8.739

2.  Hypothalamic portal blood immunoreactive TRH in the rat: lack of effect of hypothyroidism and thyroid hormone treatment.

Authors:  M C Ching; R D Utiger
Journal:  J Endocrinol Invest       Date:  1983-10       Impact factor: 4.256

3.  Histamine-containing neurons in the rat hypothalamus.

Authors:  P Panula; H Y Yang; E Costa
Journal:  Proc Natl Acad Sci U S A       Date:  1984-04       Impact factor: 11.205

4.  Influence of thyrotropin releasing hormone (TRH) on drug-induced narcosis and hypothermia in rabbits.

Authors:  A Horita; M A Carino; R M Chesnut
Journal:  Psychopharmacology (Berl)       Date:  1976-08-26       Impact factor: 4.530

5.  Effect of hypothalamic deafferentation on thyrotropin-releasing hormone levels in rat brain.

Authors:  M J Brownstein; R D Utiger; M Palkovits; J S Kizer
Journal:  Proc Natl Acad Sci U S A       Date:  1975-10       Impact factor: 11.205

6.  Amyotrophic lateral sclerosis: a double-blind crossover trial of thyrotropin-releasing hormone.

Authors:  K Imoto; K Saida; K Iwamura; T Saida; H Nishitani
Journal:  J Neurol Neurosurg Psychiatry       Date:  1984-12       Impact factor: 10.154

7.  Effects of thyrotropin-releasing hormone (TRH) and a TRH analogue, MK-771, on punished responding of squirrel monkeys.

Authors:  L S Brady; J O Valentine; J E Barrett
Journal:  Psychopharmacology (Berl)       Date:  1984       Impact factor: 4.530

8.  Plasma thyrotropin-releasing hormone concentrations in the rat. Effect of thyroid excess and deficiency and cold exposure.

Authors:  C H Emerson; R D Utiger
Journal:  J Clin Invest       Date:  1975-12       Impact factor: 14.808

9.  Effects of thyrotropin-releasing hormone (TRH) on the actions of pentobarbital and other centrally acting drugs.

Authors:  G R Breese; J M Cott; B R Cooper; A J Prange; M A Lipton; N P Plotnikoff
Journal:  J Pharmacol Exp Ther       Date:  1975-04       Impact factor: 4.030

10.  Characterization and subcellular distribution of specific thyrotropin-releasing hormone binding sites in rat cerebellum.

Authors:  C Prasad; R M Edwards
Journal:  Neurochem Res       Date:  1984-04       Impact factor: 3.996
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