Literature DB >> 4133497

Potentiation of 5-fluorouracil, chromomycin A3, and bleomycin by amphotericin B or polymyxin B in transformed fibroblastic cells.

M Kuwano, T Kamiya, H Endo, S Komiyama.   

Abstract

By using cultured, transformed fibroblastic cells, antitumor agents including cytosine arabinoside, thio-tepa, nitrogen mustard N-oxide, mitomycin C, chromomycin A3, 5-fluorouracil, daunomycin, vinblastine, vincristine, and bleomycin A2 were screened for the potentiation of their activity by amphotericin B or polymyxin B. Among them, the action of 5-fluorouracil and chromomycin A3 on ribonucleic acid synthesis was potentiated in their action by amphotericin B, not by polymyxin B. Bleomycin A2 was potentiated in its action on deoxyribonucleic acid and ribonucleic acid synthesis only by polymyxin B.

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Year:  1973        PMID： 4133497      PMCID： PMC444461          DOI： 10.1128/AAC.3.5.580

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  9 in total

Review 1.  Fluorinated pyrimidines.

Authors:  C Heidelberger
Journal:  Prog Nucleic Acid Res Mol Biol       Date:  1965

2.  Potentiation of fusidic acid and lentinan effects upon normal and transformed fibroblastic cells by amphotericin B.

Authors:  M Kuwano; S Akiyama; H Endo; M Kohga
Journal:  Biochem Biophys Res Commun       Date:  1972-12-04       Impact factor: 3.575

3.  Potentiation of drug effect by Tween 80 in Chinese hamster cells resistant to actinomycin D and daunomycin.

Authors:  H Riehm; J L Biedler
Journal:  Cancer Res       Date:  1972-06       Impact factor: 12.701

4.  Inhibition of DNA and RNA synthesis by daunorubicin in sensitive and resistant Ehrlich ascites tumor cells in vitro.

Authors:  K Dano; S Frederiksen; P Hellung-Larsen
Journal:  Cancer Res       Date:  1972-06       Impact factor: 12.701

5.  On the mechanism of action of bleomycin: scission of DNA strands in vitro and in vivo.

Authors:  H Suzuki; K Nagai; H Yamaki; N Tanaka; H Umezawa
Journal:  J Antibiot (Tokyo)       Date:  1969-09       Impact factor: 2.649

6.  New antibiotics, bleomycin A and B.

Authors:  H Umezawa; K Maeda; T Takeuchi; Y Okami
Journal:  J Antibiot (Tokyo)       Date:  1966-09       Impact factor: 2.649

7.  Biological studies on bleomycin A.

Authors:  T Ichikawa; A Matsuda; K Miyamoto; M Tsubosaki; H Umezawa
Journal:  J Antibiot (Tokyo)       Date:  1967-07       Impact factor: 2.649

8.  Potentiation of rifampicin and 5-fluorocytosine as antifungal antibiotics by amphotericin B (yeast-membrane permeability-ribosomal RNA-eukaryotic cell-synergism).

Authors:  G Medoff; G S Kobayashi; C N Kwan; D Schlessinger; P Venkov
Journal:  Proc Natl Acad Sci U S A       Date:  1972-01       Impact factor: 11.205

9.  Potentiation of the antifungal effects of antibiotics by amphotericin B.

Authors:  C N Kwan; G Medoff; G S Kobayashi; D Schlessinger; H J Raskas
Journal:  Antimicrob Agents Chemother       Date:  1972-08       Impact factor: 5.191
  9 in total
  10 in total

1.  Differential potentiation by nystatin of the effect of antibiotics on yeast and mammalian cells.

Authors:  A Aszalos
Journal:  Antimicrob Agents Chemother       Date:  1975-06       Impact factor: 5.191

2.  Properties of morphologically variant haploid frog cells formed by combined treatment with Mengo virus and the polyene antibiotic mediocidin.

Authors:  P B Fisher; N I Goldstein; V Bryson
Journal:  In Vitro       Date:  1978-12

3.  Repurposing itraconazole as an anticancer agent.

Authors:  Hiroshi Tsubamoto; Tomoko Ueda; Kayo Inoue; Kazuko Sakata; Hiroaki Shibahara; Takashi Sonoda
Journal:  Oncol Lett       Date:  2017-06-07       Impact factor: 2.967

4.  The effect of amphotericin B-deoxycholate on proliferation and protein synthesis in human skin fibroblast cultures.

Authors:  W Y Fujimoto; B J Starman; D W Rowe
Journal:  In Vitro       Date:  1978-12

5.  Reduced toxicity of amphotericin B methyl ester (AME) vs. amphotericin B and fungizone in tissue culture.

Authors:  P B Fisher; N I Goldstein; V Bryson; C P Schaffner
Journal:  In Vitro       Date:  1976-02

6.  Selection of mouse X hamster hybrids using HAT medium and a polyene antibiotic.

Authors:  N I Goldstein; P B Fisher
Journal:  In Vitro       Date:  1978-02

7.  Classification of polyene antibiotics according to their synergistic effect in combination with bleomycin A2 or fusidic acid.

Authors:  S Akiyama; T Tabuki; M Kaneko; S Komiyama; M Kuwano
Journal:  Antimicrob Agents Chemother       Date:  1980-08       Impact factor: 5.191

8.  The effect of fetal bovine serum on polyene macrolide antibiotic cytotoxicity and antifungal activity.

Authors:  D P Bonner; P B Fisher; N I Goldstein; W Mechlinski; V Bryson; C P Schaffner
Journal:  In Vitro       Date:  1976-05

9.  Potentiation of antiviral activity of acyclovir by polyene macrolide antibiotics.

Authors:  B Malewicz; M Momsen; H M Jenkin; E Borowski
Journal:  Antimicrob Agents Chemother       Date:  1984-06       Impact factor: 5.191

10.  The effect of bleomycin and pentamycin in combination on the survival of EMT6 mouse tumour cells in vitro and in vivo.

Authors:  P R Twentyman
Journal:  Br J Cancer       Date:  1976-04       Impact factor: 7.640
  10 in total

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