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Literature DB >> 4131515

Relationship between HL-A antigens and beta-2-microglobulin as studied by immunofluorescence on the lymphocyte membrane.

C Neauport-Sautes, A Bismuth, F M Kourilsky, Y Manuel.

Abstract

The antibody-induced redistribution of beta2-microglobulin (beta2-micro) and HL-A antigens on the surface of living lymphocytes was studied by immunofluorescence. When all beta2-micro was redistributed on the lymphocyte membrane by specific rabbit antibodies and goat antirabbit Ig conjugates, the HL-A antigens were no more detectable with anti-HL-A conjugates outside the beta2-micro caps already formed. However, the redistribution of HL-A antigens fails to provoke the redistribution of all detectable beta2-micro molecules. These results suggest that HL-A antigens may be associated with beta2-micro at the cell surface, but that all beta2-micro molecules are not bound to HL-A antigens.

Entities: Gene Species

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Year: 1974 PMID： 4131515 PMCID： PMC2139575 DOI： 10.1084/jem.139.4.957

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

16 in total

1. Antibody-induced redistribution of HL-A antigens at the cell surface.

Authors: F M Kourilsky; D Silvestre; C Neauport-Sautes; Y Loosfelt; J Dausset
Journal: Eur J Immunol Date: 1972-06 Impact factor: 5.532

2. The dynamic state of the lymphocyte membrane. Factors affecting the distribution and turnover of surface immunoglobulins.

Authors: F Loor; L Forni; B Pernis
Journal: Eur J Immunol Date: 1972-06 Impact factor: 5.532

3. Beta 2 -microglobulin production and secretion by lymphocytes in culture.

Authors: M D Poulik; A D Bloom
Journal: J Immunol Date: 1973-05 Impact factor: 5.422

4. Synthesis of 2 -microglobulin by stimulated lymphocytes.

Authors: G M Bernier; M W Fanger
Journal: J Immunol Date: 1972-08 Impact factor: 5.422

5. Independence of HL-A antigens and immunoglobulin determinants on the surface of human lymphoid cells.

Authors: J L Preud'homme; C Neauport-Sautes; S Piat; D Silvestre; F M Kourilsky
Journal: Eur J Immunol Date: 1972-06 Impact factor: 5.532

6. Papain-solubilized HL-A antigens from cultured human lymphocytes contain two peptide fragments.

Authors: P Cresswell; M J Turner; J L Strominger
Journal: Proc Natl Acad Sci U S A Date: 1973-05 Impact factor: 11.205

7. Initiation of protein synthesis at an unusual position in an immunoglobulin gene?

Authors: O Smithies; M D Poulik
Journal: Science Date: 1972-01-14 Impact factor: 47.728

8. The fluid mosaic model of the structure of cell membranes.

Authors: S J Singer; G L Nicolson
Journal: Science Date: 1972-02-18 Impact factor: 47.728

9. The relationship between 2 -microglobulin and immunoglobulin in cultured human lymphoid cell lines.

Authors: T H Hütteroth; H Cleve; S D Litwin; M D Poulik
Journal: J Exp Med Date: 1973-03-01 Impact factor: 14.307

10. Characterization of cystic fibrosis factor and its interaction with human immunoglobulin.

Authors: B S Danes; S D Litwin; T H Hütteroth; H Cleve; A G Bearn
Journal: J Exp Med Date: 1973-06-01 Impact factor: 14.307

11 in total

1. Immunological and chemical purity of papain-solubilized HL-A antigens.

Authors: P Parham; C Terhorst; H Herrmann; R E Humphreys; M D Waterfield; J L Strominger
Journal: Proc Natl Acad Sci U S A Date: 1975-04 Impact factor: 11.205

2. The lymphocyte plasma membrane: locus of control in the immune response.

Authors: L M Jerry; A K Sullivan
Journal: In Vitro Date: 1976-03

3. Study of human T and B lymphocytes with heterologous antisera. II. Partial characterization of a human T lymphocyte antigen.

Authors: H P Friedman; J Brochier; J P Revillard
Journal: Immunology Date: 1976-11 Impact factor: 7.397

4. Genetic and clinical studies of serum beta 2-microglobulin levels in haematological malignancies.

Authors: Y Nakao; H Matsumoto; T Miyazaki; S Watanabe; T Masaoka; K Takatsuki; M Kishihara; N Kobayashi; M Hattori; T Fujita
Journal: Clin Exp Immunol Date: 1981-10 Impact factor: 4.330

5. Human (HLA-A and HLA-B) and murine (H-2K and H-2D) histocompatibility antigens are cell surface receptors for Semliki Forest virus.

Authors: A Helenius; B Morein; E Fries; K Simons; P Robinson; V Schirrmacher; C Terhorst; J L Strominger
Journal: Proc Natl Acad Sci U S A Date: 1978-08 Impact factor: 11.205

6. Cap formation on lymphocytes from patients with leukemic diseases induced by four different lectins.

Authors: L G Gürtler; B Emmerich
Journal: Blut Date: 1978-04-20

7. Evidence for a change in the expression of beta2-microglobulin-assoicated membrane structures on leukaemic human cells.

Authors: T Plesner; H Karle; B Rubin; M Thomsen
Journal: Clin Exp Immunol Date: 1978-02 Impact factor: 4.330

8. A randomized trial to evaluate the immunorestorative properties of thymostimulin in patients with Hodgkin's disease in complete remission.

Authors: A M Liberati; E Ballatori; M Fizzotti; M Schippa; L Cini; S Cinieri; M G Proietti; R Di Marzio; M Senatore; F Grignani
Journal: Cancer Immunol Immunother Date: 1988 Impact factor: 6.968

9. Association of the H-Y male antigen with beta2-microglobulin on human lymphoid and differentiated mouse teratocarcinoma cell lines.

Authors: M Fellous; E Günther; R Kemler; J Wiels; R Berger; J L Guenet; H Jakob; F Jacob
Journal: J Exp Med Date: 1978-07-01 Impact factor: 14.307

10. Quantitative ultrastructural autoradiographic studies of iodinated plasma membranes of lymphocytes during segregation and internalization of surface immunoglobulins.

Authors: N K Gonatas; J O Gonatas; A Stieber; J C Antoine; S Avrameas
Journal: J Cell Biol Date: 1976-09 Impact factor: 10.539