Literature DB >> 412109

Endogenous inhibitor of prostaglandin synthetase.

S A Saeed, W J McDonald-Gibson, J Cuthbert, J L Copas, C Schneider, P J Gardiner, N M Butt, H O Collier.   

Abstract

Mammalian serum and plasma contain an endogenous inhibitor of prostaglandin synthetase (EIPS). Human plasma fractions rich in EIPS show anti-inflammatory activity in vivo. In rats, glucocorticoids raise EIPS activity of plasma and serum. These findings suggest the existence of a natural mechanism of controlling prostaglandin synthesis, possibly related to corticosteroid action.

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Year:  1977        PMID： 412109     DOI： 10.1038/270032a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  17 in total

1.  Fever response of sheep in the peripartum period to gram-negative and gram-positive pyrogens.

Authors:  K Goelst; D Mitchell; A P MacPhail; K E Cooper; H Laburn
Journal:  Pflugers Arch       Date:  1992-03       Impact factor: 3.657

2.  The effects of antiinflammatory steroids on arachidonate metabolism and prostaglandin synthesis vary according to culture conditions.

Authors:  D Duval; J F Huneau; F Homo-Delarche
Journal:  Agents Actions       Date:  1986-01

3.  Animal models for the study of atypical anti-inflammatory agents.

Authors:  B Silvestrini
Journal:  Agents Actions       Date:  1986-01

4.  Dual inhibition of cyclooxygenase and lipoxygenase enzymes by human cerebrospinal fluid.

Authors:  Sheikh Arshad Saeed; Kaneez Fatima Shad; Shabana Usman Simjee
Journal:  Exp Brain Res       Date:  2007-03-20       Impact factor: 1.972

5.  Influence of hydrocortisone on the modulation of the inflammatory response.

Authors:  G Tolone; L Bonasera; C Tolone
Journal:  Br J Exp Pathol       Date:  1978-08

6.  Characterization and partial purification of 'renocortins': two polypeptides formed in renal cells causing the anti-phospholipase-like action of glucocorticoids.

Authors:  J F Cloix; O Colard; B Rothhut; F Russo-Marie
Journal:  Br J Pharmacol       Date:  1983-05       Impact factor: 8.739

7.  Endogenous inhibitor of prostaglandin biosynthesis in inflammation.

Authors:  M Di Rosa; F Capasso; N Mascolo
Journal:  Agents Actions       Date:  1980-09

8.  Purification of haptoglobin and its effects on lymphocyte and alveolar macrophage responses.

Authors:  M W Baseler; R Burrell
Journal:  Inflammation       Date:  1983-12       Impact factor: 4.092

9.  Glucocorticoid protection against PAF-acether toxicity in mice.

Authors:  A Myers; E Ramey; P Ramwell
Journal:  Br J Pharmacol       Date:  1983-06       Impact factor: 8.739

10.  Glucocorticoids induce the formation and release of anti-inflammatory and anti-phospholipase proteins into the peritoneal cavity of the rat.

Authors:  G J Blackwell; R Carnuccio; M Di Rosa; R J Flower; C S Langham; L Parente; P Persico; N C Russel-Smith; D Stone
Journal:  Br J Pharmacol       Date:  1982-05       Impact factor: 8.739
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