Literature DB >> 411713

Genetics of cycloheximide resistance in Tetrahymena.

L K Bleyman, P J Bruns.   

Abstract

Cycloheximide resistance in Tetrahymena is inducible by mutagenesis. Two mutations, isolated independently from genetically different strains, were analyzed. The two mutations, Chx-1 and Chx-2, were found to be alleles at the same locus. A specific analysis is presented which may serve as a model for strategies employing an independent manipulation of the micro-and macronuclei of this organism for genetic studies.

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Year:  1977        PMID： 411713      PMCID： PMC1213740     

Source DB:  PubMed          Journal:  Genetics        ISSN： 0016-6731            Impact factor:   4.562


  4 in total

1.  A Temperature-Sensitive Mutant in TETRAHYMENA PYRIFORMIS, Syngen 1.

Authors:  J W McCoy
Journal:  Genetics       Date:  1973-05       Impact factor: 4.562

2.  Costimulation in Tetrahymena pyriformis: a developmental interaction between specially prepared cells.

Authors:  P J Bruns; R F Palestine
Journal:  Dev Biol       Date:  1975-01       Impact factor: 3.582

3.  Positive selection for mating with functional heterokaryons in Tetrahymena pyriformis.

Authors:  P J Bruns; T B Brussard
Journal:  Genetics       Date:  1974-11       Impact factor: 4.562

4.  Mutations affecting cell division in Tetrahymena pyriformis. I. Selection and genetic analysis.

Authors:  J Frankel; L M Jenkins; F P Doerder; E M Nelsen
Journal:  Genetics       Date:  1976-07       Impact factor: 4.562
  4 in total
  12 in total

1.  Transformation of Tetrahymena to cycloheximide resistance with a ribosomal protein gene through sequence replacement.

Authors:  M C Yao; C H Yao
Journal:  Proc Natl Acad Sci U S A       Date:  1991-11-01       Impact factor: 11.205

2.  A drug-resistant mutation in the ribosomal DNA of Tetrahymena.

Authors:  P J Bruns; A L Katzen; L Martin; E H Blackburn
Journal:  Proc Natl Acad Sci U S A       Date:  1985-05       Impact factor: 11.205

3.  Mass isolation and fertility testing of temperature-sensitive mutants in Tetrahymena.

Authors:  P J Bruns; Y M Sanford
Journal:  Proc Natl Acad Sci U S A       Date:  1978-07       Impact factor: 11.205

4.  Properties of the translocatable tetracycline-resistance element Tn10 in Escherichia coli and bacteriophage lambda.

Authors:  N Kleckner; D F Barker; D G Ross; D Botstein
Journal:  Genetics       Date:  1978-11       Impact factor: 4.562

5.  Phenotypic assortment in Tetrahymena thermophila: assortment kinetics of antibiotic-resistance markers, tsA, death, and the highly amplified rDNA locus.

Authors:  E V Merriam; P J Bruns
Journal:  Genetics       Date:  1988-10       Impact factor: 4.562

6.  Mutants of TETRAHYMENA THERMOPHILA with Temperature-Sensitive Food Vacuole Formation. I. Isolation and Genetic Characterization.

Authors:  P B Suhr-Jessen; E Orias
Journal:  Genetics       Date:  1979-08       Impact factor: 4.562

7.  Cycloheximide-resistance in Chinese hamster ovary cells and human fibroblast cells. Cytogenetic and biochemical characterization.

Authors:  H Pöche; K H Nierhaus; S Zakrzewski
Journal:  Hum Genet       Date:  1979-09       Impact factor: 4.132

8.  Isolation and genetic characterization of a mutation affecting ribosomal resistance to cycloheximide in Tetrahymena.

Authors:  M Ares; P J Bruns
Journal:  Genetics       Date:  1978-11       Impact factor: 4.562

9.  Cycloheximide resistance can be mediated through either ribosomal subunit.

Authors:  C A Sutton; M Ares; R L Hallberg
Journal:  Proc Natl Acad Sci U S A       Date:  1978-07       Impact factor: 11.205

10.  Induced resistance to 6-methylpurine and cycloheximide in tetrahymena. I. Germ line mutants of T. thermophila.

Authors:  B C Byrne; T B Brussard; P J Bruns
Journal:  Genetics       Date:  1978-08       Impact factor: 4.562
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