Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The nature of the alkaline phosphatases of bile.

Literature DB >> 4111711

The nature of the alkaline phosphatases of bile.

Abstract

The main alkaline phosphatase isoenzymes of human bile have been purified by DEAE-cellulose chromatography. Characteristics of the isoenzymes, such as electrophoretic mobility before and after butanol extraction, Michaelis constant, and change in electrophoretic mobility following exposure to neuraminidase have been studied and compared with isoenzymes from other sources. The results show that the main alkaline phosphatase of bile is derived from the liver. It is present as a protein phosphatidylcholine complex.

Entities: Chemical Gene Species

Mesh：

Substances：

Year: 1972 PMID： 4111711 PMCID： PMC477245 DOI： 10.1136/jcp.25.2.149

Source DB: PubMed Journal: J Clin Pathol ISSN： 0021-9746 Impact factor: 3.411

14 in total

1. Serum alkaline phosphatase fractions in hepato-biliary and bone diseases.

Authors: L CHIANDUSSI; S F GREENE; S SHERLOCK
Journal: Clin Sci Date: 1962-06 Impact factor: 6.124

2. Iso-enzymes of alkaline phosphatase.

Authors: A W HODSON; A L LATNER; L RAINE
Journal: Clin Chim Acta Date: 1962-03 Impact factor: 3.786

3. Studies on alkaline phosphatases. 2. Factors influencing pH optima and Michaelis constant.

Authors: I MOTZOK; H D BRANION
Journal: Biochem J Date: 1959-05 Impact factor: 3.857

4. The estimation of true lipase in small intestinal contents.

Authors: A C FRAZER; H G SAMMONS; M THOMPSON
Journal: J Clin Pathol Date: 1956-11 Impact factor: 3.411

5. Metabolism and excretion of alkaline phosphatase: relation to liver function and determination of maximal secretory rates of liver.

Authors: H H LeVEEN; L J TALBOT; M RESTUCCIA; J R BARBERIO
Journal: J Lab Clin Med Date: 1950-08

6. Quantitative analysis of phospholipids by thin-layer chromatography.

Authors: V P Skipski; R F Peterson; M Barclay
Journal: Biochem J Date: 1964-02 Impact factor: 3.857

7. Value of differential thermostability, urea inhibition, and gel filtration of alkaline phosphatase in the identification of disease states.

Authors: J J Fennelly; M X Fitzgerald; K McGeeney
Journal: Gut Date: 1969-01 Impact factor: 23.059

8. An interpretation of the elevation of serum alkaline phosphatase in disease.

Authors: P G Hill; H G Sammons
Journal: J Clin Pathol Date: 1967-07 Impact factor: 3.411

9. The behavior of infused human placental alkaline phosphatase in human subjects.

Authors: J S Clubb; F C Neale; S Posen
Journal: J Lab Clin Med Date: 1965-09

10. Protein characteristics of serum and bile alkaline phosphatase.

Authors: C E Pope; S R Cooperband
Journal: Gastroenterology Date: 1966-05 Impact factor: 22.682

8 in total

1. An interpretation of the serum alkaline phosphatase isoenzyme patterns in patients with obstructive liver disease.

Authors: C P Price; H G Sammons
Journal: J Clin Pathol Date: 1976-11 Impact factor: 3.411

2. gamma-Glutamyl transferase isoenzymes in human bile.

Authors: P R Wenham; C P Price; H G Sammons
Journal: J Clin Pathol Date: 1978-07 Impact factor: 3.411

3. The nature of the serum alkaline phosphatases in liver diseases.

Authors: C P Price; H G Sammons
Journal: J Clin Pathol Date: 1974-05 Impact factor: 3.411

4. Serum gamma-glutamyltransferase isoenzymes in extrahepatic biliary obstruction.

Authors: P R Wenham; C P Price; H G Sammons
Journal: J Clin Pathol Date: 1979-09 Impact factor: 3.411

5. Electron microscopic studies on hepatic alkaline phosphatase in experimentally induced biliary obstruction of the rat.

Authors: M Kako; G Toda; M Torii; H Kimura; K Miyake; H Suzuki; T Oda
Journal: Gastroenterol Jpn Date: 1980

6. Intestinal alkaline phosphatase in bile: evidence for an enterohepatic circulation.

Authors: T W Warnes; P Hine; G Kay; A Smith
Journal: Gut Date: 1981-06 Impact factor: 23.059

7. Enzymes and proteins in bile. Variations in output in rat cannula bile during and after depletion of the bile-salt pool.

Authors: P P Godfrey; M J Warner; R Coleman
Journal: Biochem J Date: 1981-04-15 Impact factor: 3.857

8. Clinical enzymology.

Authors: J H Wilkinson
Journal: J R Soc Med Date: 1978-04 Impact factor: 18.000

8 in total