Literature DB >> 27536

gamma-Glutamyl transferase isoenzymes in human bile.

P R Wenham, C P Price, H G Sammons.   

Abstract

The gamma-glutamyl transferase isoenzymes of bile were studied using electrophoretic, gel filtration, and ultracentrifugation techniques. In view of the known association of other biliary enzymes with lipids the effects of butanol extraction were investigated. The results show the presence of four isoenzymes of gamma-glutamyl transferase in bile, differing in electrophoretic mobilities, molecular size, and density. The correlation between the properties of biliary gamma-glutamyl transferase and of alkaline phosphatase is discussed.

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Year:  1978        PMID: 27536      PMCID: PMC1145371          DOI: 10.1136/jcp.31.7.666

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN: 0021-9746            Impact factor:   3.411


  15 in total

1.  SERUM GAMMA-GLUTAMYL TRANSPEPTIDASE ACTIVITY IN HEPATOBILIARY PANCREATIC DISEASE.

Authors:  A M RUTTENBURG; J A GOLDBARG; E P PINEDA
Journal:  Gastroenterology       Date:  1963-07       Impact factor: 22.682

2.  THE ROLE OF GAMMA-GLUTAMYL TRANSPEPTIDASE IN THE INTERNAL DISEASES CLINIC.

Authors:  M ORLOWSKI
Journal:  Arch Immunol Ther Exp (Warsz)       Date:  1963       Impact factor: 4.291

3.  Iso-enzymes of alkaline phosphatase in autolysed and butanol-extracted liver preparations.

Authors:  D W MOSS
Journal:  Nature       Date:  1962-03-10       Impact factor: 49.962

4.  The heterogeneity of the serum activity of gamma-glutamyl transpeptidase in hepatobiliary diseases as studied by agarose gel electrophoresis.

Authors:  O Hetland; T R Andersson; T Gerner
Journal:  Clin Chim Acta       Date:  1975-08-04       Impact factor: 3.786

Review 5.  A short review of techniques for the localisation of gamma-glutamyl transferase isoenzymes after electrophoresis.

Authors:  P R Wenham; C P Price; H G Sammons
Journal:  Ann Clin Biochem       Date:  1978-05       Impact factor: 2.057

6.  The nature of the alkaline phosphatases of bile.

Authors:  C P Price; P G Hill; H G Sammons
Journal:  J Clin Pathol       Date:  1972-02       Impact factor: 3.411

7.  Enzyme changes in experimental biliary obstruction.

Authors:  A J Kryszewski; G Neale; J B Whitfield; D W Moss
Journal:  Clin Chim Acta       Date:  1973-08-30       Impact factor: 3.786

8.  Optimized determination of gamma-glutamyltransferase by reaction-rate analysis.

Authors:  S B Rosalki; D Tarlow
Journal:  Clin Chem       Date:  1974-09       Impact factor: 8.327

9.  Separation of alkaline phosphatase enzymes in human serum using gel-filtration (Sephadex G-200) techniques.

Authors:  J Dunne; J J Fennelly; K McGeeney
Journal:  Cancer       Date:  1967-01       Impact factor: 6.860

10.  The separation and characterization of liver plasma membrane fragments circulating in the blood of patients with cholestasis.

Authors:  M E De Broe; M Borgers; R J Wieme
Journal:  Clin Chim Acta       Date:  1975-03-24       Impact factor: 3.786

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  1 in total

1.  Serum gamma-glutamyltransferase isoenzymes in extrahepatic biliary obstruction.

Authors:  P R Wenham; C P Price; H G Sammons
Journal:  J Clin Pathol       Date:  1979-09       Impact factor: 3.411

  1 in total

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