Literature DB >> 1002841

An interpretation of the serum alkaline phosphatase isoenzyme patterns in patients with obstructive liver disease.

C P Price, H G Sammons.   

Abstract

Earlier studies have identified two main isoenzymes of alkaline phosphatase in the sera of patients with obstructive liver disease. This paper reports on a study of these isoenzymes in specific types of liver disease where the pathology in relation to bile duct obstruction is known. The results have been used to support the theory that in biliary obstruction the increase in serum alkaline phosphatase is in part due to regurgitation of the biliary isoenzymes.

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Year:  1976        PMID： 1002841      PMCID： PMC476248          DOI： 10.1136/jcp.29.11.976

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  19 in total

1.  The effects of experimental acute biliary obstruction and release on the rat liver. A histochemical study.

Authors:  M BIRNS; B MASEK; O AUERBACH
Journal:  Am J Pathol       Date:  1962-01       Impact factor: 4.307

2.  Serum alkaline phosphatase fractions in hepato-biliary and bone diseases.

Authors:  L CHIANDUSSI; S F GREENE; S SHERLOCK
Journal:  Clin Sci       Date:  1962-06       Impact factor: 6.124

3.  Serum alkaline phosphatase activity in diseases of the skeletal and hepatobiliary systems. A consideration of the current status.

Authors:  A B GUTMAN
Journal:  Am J Med       Date:  1959-12       Impact factor: 4.965

4.  Substrate specific phosphatases at pH 7.2 in biliary obstruction and liver cell damage; special reference to the bile canaliculi in obstructive jaundice and liver-cell necrosis.

Authors:  M WACHSTEIN; E MEISEL
Journal:  AMA Arch Pathol       Date:  1958-04

5.  Intrahepatic cholestasis (cholangiolitis).

Authors:  H POPPER; P B SZANTO
Journal:  Gastroenterology       Date:  1956-12       Impact factor: 22.682

6.  Estimation of plasma phosphatase by determination of hydrolysed phenol with amino-antipyrine.

Authors:  P R KIND; E J KING
Journal:  J Clin Pathol       Date:  1954-11       Impact factor: 3.411

7.  The origin of elevation of serum alkaline phosphatase in hepatic disease. An experimental study.

Authors:  S G POLIN; M A SPELLBERG; L TEITELMAN; M OKUMURA
Journal:  Gastroenterology       Date:  1962-04       Impact factor: 22.682

8.  The nature of the alkaline phosphatases of bile.

Authors:  C P Price; P G Hill; H G Sammons
Journal:  J Clin Pathol       Date:  1972-02       Impact factor: 3.411

9.  The nature of the serum alkaline phosphatases in liver diseases.

Authors:  C P Price; H G Sammons
Journal:  J Clin Pathol       Date:  1974-05       Impact factor: 3.411

10.  Induction of rat liver alkaline phosphatase: the mechanism of the serum elevation in bile duct obstruction.

Authors:  M M Kaplan; A Righetti
Journal:  J Clin Invest       Date:  1970-03       Impact factor: 14.808
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  2 in total

1.  The preparation of monoclonal antibodies to human bone and liver alkaline phosphatase and their use in immunoaffinity purification and in studying these enzymes when present in serum.

Authors:  E M Bailyes; R N Seabrook; J Calvin; G A Maguire; C P Price; K Siddle; J P Luzio
Journal:  Biochem J       Date:  1987-06-15       Impact factor: 3.857

2.  Serum Alkaline Phosphatase in Cryptogenic Stroke Cases with Active Cancer.

Authors:  Tesseki Izumi; Hitoki Nanaura; Naohiko Iguchi; Maki Ozaki; Kazuma Sugie
Journal:  Intern Med       Date:  2022-03-01       Impact factor: 1.271
  2 in total

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