Literature DB >> 4074339

Glycolytic origin of alanine formed in rat diaphragm muscle in vitro.

M A Caldecourt, D J Cox, M C Sugden, T N Palmer.   

Abstract

In quarter-diaphragms from 40 h-starved rats the rate of glycogen mobilization is sufficient to account for the rate of lactate+pyruvate+alanine production. It is concluded, therefore, that alanine derives its carbon skeleton predominantly via glycolysis and not via synthesis de novo from tricarboxylic acid-cycle intermediates and related amino acids.

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Year:  1985        PMID： 4074339      PMCID： PMC1152823          DOI： 10.1042/bj2310801

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  16 in total

Review 1.  Amino acid metabolism in man.

Authors:  P Felig
Journal:  Annu Rev Biochem       Date:  1975       Impact factor: 23.643

2.  The formation of alanine from amino acids in diaphragm muscle of the rat.

Authors:  L Goldstein; E A Newsholme
Journal:  Biochem J       Date:  1976-02-15       Impact factor: 3.857

3.  The metabolic fates of amino acids and the formation of glutamine in skeletal muscle.

Authors:  T W Chang; A L Goldberg
Journal:  J Biol Chem       Date:  1978-05-25       Impact factor: 5.157

4.  The origin of alanine produced in skeletal muscle.

Authors:  T W Chang; A L Goldberg
Journal:  J Biol Chem       Date:  1978-05-25       Impact factor: 5.157

5.  Leucine inhibits oxidation of glucose and pyruvate in skeletal muscles during fasting.

Authors:  T W Chang; A L Goldberg
Journal:  J Biol Chem       Date:  1978-05-25       Impact factor: 5.157

Review 6.  Muscle alanine synthesis and hepatic gluconeogenesis.

Authors:  K Snell
Journal:  Biochem Soc Trans       Date:  1980-04       Impact factor: 5.407

7.  The role of phosphoenolpyruvate carboxykinase in muscle alanine synthesis.

Authors:  T N Palmer; M A Caldecourt; J P Warner; M C Sugden
Journal:  Biochem J       Date:  1984-12-15       Impact factor: 3.857

8.  Enzymic determination of branched-chain amino acids and 2-oxoacids in rat tissues. Transfer of 2-oxoacids from skeletal muscle to liver in vivo.

Authors:  G Livesey; P Lund
Journal:  Biochem J       Date:  1980-06-15       Impact factor: 3.857

9.  The release of alanine by rat diaphragm muscle in vitro.

Authors:  K Snell; D A Duff
Journal:  Biochem J       Date:  1977-02-15       Impact factor: 3.857

10.  The effect of octanoate and palmitate on the metabolism of valine in perfused hindquarter of rat.

Authors:  O Spydevold
Journal:  Eur J Biochem       Date:  1979-07
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  2 in total

1.  The effect of ketone bodies on alanine and glutamine metabolism in isolated skeletal muscle from the fasted chick.

Authors:  G Y Wu; J R Thompson
Journal:  Biochem J       Date:  1988-10-01       Impact factor: 3.857

2.  The regulation of glutamine and ketone-body metabolism in the small intestine of the long-term (40-day) streptozotocin-diabetic rat.

Authors:  M Watford; E J Erbelding; E M Smith
Journal:  Biochem J       Date:  1987-02-15       Impact factor: 3.857
  2 in total

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