| Literature DB >> 4041021 |
A Oliverio, C Castellano, S Puglisi-Allegra, P Renzi.
Abstract
Electroconvulsive shock (ECS)-induced seizures present a clear cut diurnal rhythmicity when BALB/c mice are subjected to a light-dark (L/D) schedule. On the contrary, in the absence of external synchronizers no evident fluctuations in epileptic behaviour were evident. Naloxone decreased the threshold of ECS-induced convulsions, thus confirming an involvement of opioids in this type of behaviour. These findings indicate that opioids present a diurnal (L/D) but not circadian (L/L) rhythmicity in BALB/c mice.Entities:
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Year: 1985 PMID: 4041021 DOI: 10.1016/0304-3940(85)90497-5
Source DB: PubMed Journal: Neurosci Lett ISSN: 0304-3940 Impact factor: 3.046