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Literature DB >> 402672

Intracranial reward after Lilly 110140 (fluoxetine HCl): evidence for an inhibitory role for serotonin.

Abstract

The 5-hydroxytryptamine (5-HT, serotonin) specific presynaptic reuptake inhibitor Lilly 110140 (fluoxetine hydroxhloride) was injected systemically in rats trained to bar-press for rewarding stimulation to the caudal portion of the medial forebrain bundle. Rates of self stimulation were reduced in proportion to drug dosage, and these reductions were partially reversible by methysergide. These findings are consistent with previous reports suggesting an inhibitory role for 5-HT in self stimulation.

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Year: 1977 PMID： 402672 DOI： 10.1007/bf00431739

Source DB: PubMed Journal: Psychopharmacology (Berl) ISSN： 0033-3158 Impact factor: 4.530

39 in total

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Authors: R W Fuller; K W Perry
Journal: J Pharm Pharmacol Date: 1975-08 Impact factor: 3.765

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Authors: E Miliaressis; D M Jacobowitz
Journal: Pharmacol Biochem Behav Date: 1976-04 Impact factor: 3.533

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Authors: S Bose; P T Bailey; N B Thoa; S N Pradhan
Journal: Psychopharmacologia Date: 1974-04-23

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Journal: Life Sci Date: 1974-09-15 Impact factor: 5.037

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Journal: Psychol Med Date: 1972-11 Impact factor: 7.723

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Authors: H J Haigler; G K Aghajanian
Journal: J Neural Transm Date: 1974 Impact factor: 3.575

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Authors: R W Fuller; K W Perry; H D Snoddy; B B Molloy
Journal: Eur J Pharmacol Date: 1974-09 Impact factor: 4.432

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Journal: Acta Physiol Scand Suppl Date: 1971

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Journal: Life Sci Date: 1968-03-01 Impact factor: 5.037

13 in total

1. Responding for a conditioned reinforcer or unconditioned sensory reinforcer in mice: interactions with environmental enrichment, social isolation, and monoamine reuptake inhibitors.

Authors: Caleb J Browne; Paul J Fletcher; Fiona D Zeeb
Journal: Psychopharmacology (Berl) Date: 2015-12-22 Impact factor: 4.530

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Authors: Sergio D Iñiguez; Brandon L Warren; Carlos A Bolaños-Guzmán
Journal: Biol Psychiatry Date: 2010-02-20 Impact factor: 13.382

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Journal: Pharmacol Rev Date: 2014-07 Impact factor: 25.468

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Authors: John F Cryan; Adrie W Bruijnzeel; Karen L Skjei; Athina Markou
Journal: Psychopharmacology (Berl) Date: 2003-04-16 Impact factor: 4.530

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Authors: Martin Weber; Sonja Talmon; Ilka Schulze; Christine Boeddinghaus; Gerhard Gross; Hans Schoemaker; Karsten M Wicke
Journal: Psychopharmacology (Berl) Date: 2008-12-23 Impact factor: 4.530

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Authors: P Benfield; R C Heel; S P Lewis
Journal: Drugs Date: 1986-12 Impact factor: 9.546