Literature DB >> 4022775

Human DNA sequences exhibiting gamete-specific hypomethylation.

X Y Zhang, R Y Wang, M Ehrlich.   

Abstract

Three human DNA sequences have been cloned from DNA regions which are strikingly undermethylated in sperm, highly methylated in adult somatic tissues, and methylated to an intermediate extent in tissues of extraembryonic origin. It is proposed that some such DNA sequences may function specifically early in embryogenesis or during gametogenesis. They may be subsequently extensively methylated in the embryonic cell lineage and methylated to a lesser extent in extraembryonic tissues in order to allow embryogenesis to proceed.

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Year:  1985        PMID： 4022775      PMCID： PMC321830          DOI： 10.1093/nar/13.13.4837

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  23 in total

1.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

2.  Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

Authors:  P W Rigby; M Dieckmann; C Rhodes; P Berg
Journal:  J Mol Biol       Date:  1977-06-15       Impact factor: 5.469

3.  A fraction of the mouse genome that is derived from islands of nonmethylated, CpG-rich DNA.

Authors:  A Bird; M Taggart; M Frommer; O J Miller; D Macleod
Journal:  Cell       Date:  1985-01       Impact factor: 41.582

4.  The use of heparin as a simple cost-effective means of controlling background in nucleic acid hybridization procedures.

Authors:  L Singh; K W Jones
Journal:  Nucleic Acids Res       Date:  1984-07-25       Impact factor: 16.971

5.  Characterization of highly and moderately repetitive 500 bp Eco RI fragments from Xenopus laevis DNA.

Authors:  S Hummel; W Meyerhof; E Korge; W Knöchel
Journal:  Nucleic Acids Res       Date:  1984-06-25       Impact factor: 16.971

Review 6.  5-Methylcytosine in eukaryotic DNA.

Authors:  M Ehrlich; R Y Wang
Journal:  Science       Date:  1981-06-19       Impact factor: 47.728

7.  Sequence definition and organization of a human repeated DNA.

Authors:  J C Wu; L Manuelidis
Journal:  J Mol Biol       Date:  1980-09-25       Impact factor: 5.469

8.  Comparative analysis of three guinea pig satellite DNA's by restriction nucleases.

Authors:  W Altenburger; W Hörz; H G Zachau
Journal:  Eur J Biochem       Date:  1977-03-01

9.  A membrane-filter technique for the detection of complementary DNA.

Authors:  D T Denhardt
Journal:  Biochem Biophys Res Commun       Date:  1966-06-13       Impact factor: 3.575

10.  Two sequence-specific endonucleases from Xanthomonas oryzae. Characterization and unusual properties.

Authors:  R Y Wang; J G Shedlarski; M B Farber; D Kuebbing; M Ehrlich
Journal:  Biochim Biophys Acta       Date:  1980-02-29
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  5 in total

1.  Hypermethylation of human DNA sequences in embryonal carcinoma cells and somatic tissues but not in sperm.

Authors:  X Y Zhang; P T Loflin; C W Gehrke; P A Andrews; M Ehrlich
Journal:  Nucleic Acids Res       Date:  1987-11-25       Impact factor: 16.971

Review 2.  Facioscapulohumeral muscular dystrophy (FSHD): an enigma unravelled?

Authors:  Mark Richards; Frédérique Coppée; Nick Thomas; Alexandra Belayew; Meena Upadhyaya
Journal:  Hum Genet       Date:  2011-10-09       Impact factor: 4.132

3.  Characterization of mutations induced by ethylnitrosourea in seminiferous tubule germ cells of transgenic B6C3F1 mice.

Authors:  G S Provost; J M Short
Journal:  Proc Natl Acad Sci U S A       Date:  1994-07-05       Impact factor: 11.205

4.  Methylation of chick UbI and UbII polyubiquitin genes and their differential expression during spermatogenesis.

Authors:  N Rocamora; N Agell
Journal:  Biochem J       Date:  1990-05-01       Impact factor: 3.857

5.  Fundamental diversity of human CpG islands at multiple biological levels.

Authors:  Jia Zeng; Hema K Nagrajan; Soojin V Yi
Journal:  Epigenetics       Date:  2014-01-13       Impact factor: 4.528
  5 in total

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