Literature DB >> 4006914

Transcripts from an aberrantly re-arranged human T-cell receptor beta-chain gene.

M K Collins, A M Kissonerghis, M J Dunne, C J Watson, P W Rigby, M J Owen.   

Abstract

A number of cDNA clones homologous to the human T-cell receptor beta-chain gene have been isolated from a library constructed from the human leukaemic cell line Jurkat. The nucleotide sequences of two of these clones demonstrate that Jurkat synthesizes an RNA, probably derived from an aberrantly rearranged C beta 1 gene, which cannot encode a functional beta-chain. This transcript contains a novel joining region and similar transcripts appear to be relatively abundant in several T-cell lines.

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Year:  1985        PMID： 4006914      PMCID： PMC554326          DOI： 10.1002/j.1460-2075.1985.tb03762.x

Source DB:  PubMed          Journal:  EMBO J        ISSN： 0261-4189            Impact factor:   11.598


  24 in total

1.  Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose.

Authors:  P S Thomas
Journal:  Proc Natl Acad Sci U S A       Date:  1980-09       Impact factor: 11.205

2.  Isolation of cDNA clones encoding T cell-specific membrane-associated proteins.

Authors:  S M Hedrick; D I Cohen; E A Nielsen; M M Davis
Journal:  Nature       Date:  1984 Mar 8-14       Impact factor: 49.962

3.  A simple and very efficient method for generating cDNA libraries.

Authors:  U Gubler; B J Hoffman
Journal:  Gene       Date:  1983-11       Impact factor: 3.688

4.  The mouse T cell receptor: structural heterogeneity of molecules of normal T cells defined by xenoantiserum.

Authors:  B W McIntyre; J P Allison
Journal:  Cell       Date:  1983-10       Impact factor: 41.582

5.  Complexity of human T-cell antigen receptor beta-chain constant- and variable-region genes.

Authors:  J E Sims; A Tunnacliffe; W J Smith; T H Rabbitts
Journal:  Nature       Date:  1984 Dec 6-12       Impact factor: 49.962

6.  Differential expression of the members of the discoidin I multigene family during growth and development of Dictyostelium discoideum.

Authors:  J M Devine; A S Tsang; J G Williams
Journal:  Cell       Date:  1982-04       Impact factor: 41.582

7.  The human T cell receptor: appearance in ontogeny and biochemical relationship of alpha and beta subunits on IL-2 dependent clones and T cell tumors.

Authors:  O Acuto; R E Hussey; K A Fitzgerald; J P Protentis; S C Meuer; S F Schlossman; E L Reinherz
Journal:  Cell       Date:  1983-10       Impact factor: 41.582

8.  The mouse T cell receptor: comparison of MHC-restricted receptors on two T cell hybridomas.

Authors:  J Kappler; R Kubo; K Haskins; J White; P Marrack
Journal:  Cell       Date:  1983-10       Impact factor: 41.582

9.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

10.  A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains.

Authors:  Y Yanagi; Y Yoshikai; K Leggett; S P Clark; I Aleksander; T W Mak
Journal:  Nature       Date:  1984 Mar 8-14       Impact factor: 49.962
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  9 in total

1.  CD3+ CD57+ lymphocytes are not likely to be involved in antigen-specific rejection processes in long-term allograft recipients.

Authors:  B Reipert; C Scheuch; A Lukowsky; P Reinke; E Fietze; W D Döcke; G Staffa; S Czerlinksi; R Hetzer; H D Volk
Journal:  Clin Exp Immunol       Date:  1992-07       Impact factor: 4.330

2.  T-cell receptor V beta 5 usage defines reactivity to a human T-cell receptor monoclonal antibody.

Authors:  M Lipoldova; A W Boylston; H Yssel; M J Owen
Journal:  Immunogenetics       Date:  1989       Impact factor: 2.846

3.  Clonal analysis of childhood acute lymphoblastic leukemia with "cytogenetically independent" cell populations.

Authors:  C H Pui; W H Raskind; G R Kitchingman; S C Raimondi; F G Behm; S B Murphy; W M Crist; P J Fialkow; D L Williams
Journal:  J Clin Invest       Date:  1989-06       Impact factor: 14.808

4.  Provocative pattern of rearrangements of the genes for the gamma and beta chains of the T-cell receptor in human leukemias.

Authors:  R Goorha; N Bunin; J Mirro; S B Murphy; A H Cross; F G Behm; T Quertermous; J Seidman; G R Kitchingman
Journal:  Proc Natl Acad Sci U S A       Date:  1987-07       Impact factor: 11.205

5.  T-cell receptor beta gene rearrangements in clones derived from human CD4-8- cells expressing natural killer cell activity.

Authors:  S E Christmas; M Moore
Journal:  Immunology       Date:  1988-12       Impact factor: 7.397

6.  Sequence of the D beta 2-J beta 2 region of the human T-cell receptor beta-chain locus.

Authors:  A Tunnacliffe; T H Rabbitts
Journal:  Nucleic Acids Res       Date:  1985-09-25       Impact factor: 16.971

7.  Large granular lymphocyte expansions in patients with Felty's syndrome: analysis using anti-T cell receptor V beta-specific monoclonal antibodies.

Authors:  S J Bowman; M Bhavnani; G C Geddes; V Corrigall; A W Boylston; G S Panayi; J S Lanchbury
Journal:  Clin Exp Immunol       Date:  1995-07       Impact factor: 4.330

8.  Expression of T cell receptor genes in human B cells.

Authors:  A F Calman; B M Peterlin
Journal:  J Exp Med       Date:  1986-12-01       Impact factor: 14.307

9.  In situ hybridisation and S1 mapping show that the presence of infiltrating plasma cells is associated with poor prognosis in breast cancer.

Authors:  H Parkes; P Collis; A Baildam; D Ralphs; B Lyons; A Howell; R Craig
Journal:  Br J Cancer       Date:  1988-12       Impact factor: 7.640
  9 in total

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