Literature DB >> 4002248

Development of reflexes in neonatal mice prenatally exposed to methylmercury and selenite.

H Satoh, N Yasuda, S Shimai.   

Abstract

The development of reflexes in neonates exposed prenatally to methylmercury and selenite was investigated. Pregnant mice were assigned to one of 4 treatments; methylmercury (MeHg), selenite(Se), combination of 2 compounds (MeHg X Se) and saline control (NaCl). Mice were injected subcutaneously (s.c.) on day 9 of gestation. The dose of each compound was 30 mumol/kg. Mercury (Hg) concentrations in the neonatal brain and liver of the MeHg X Se group were slightly lower than in the MeHg group. The results of behavioral examination revealed that the MeHg X Se group showed significantly improved development compared with the MeHg group. These facts suggest the possibility that selenium compounds have protective effects against methylmercury neurotoxicity in fetuses and neonates.

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Year:  1985        PMID： 4002248     DOI： 10.1016/0378-4274(85)90082-7

Source DB:  PubMed          Journal:  Toxicol Lett        ISSN： 0378-4274            Impact factor:   4.372


  15 in total

1.  Interspecific and intraspecific variation in selenium:mercury molar ratios in saltwater fish from the Aleutians: potential protection on mercury toxicity by selenium.

Authors:  Joanna Burger; Michael Gochfeld; Christian Jeitner; Mark Donio; Taryn Pittfield
Journal:  Sci Total Environ       Date:  2012-06-03       Impact factor: 7.963

2.  Selenium and mercury molar ratios in saltwater fish from New Jersey: individual and species variability complicate use in human health fish consumption advisories.

Authors:  Joanna Burger; Michael Gochfeld
Journal:  Environ Res       Date:  2012-03-09       Impact factor: 6.498

3.  Gestational exposure to methylmercury and selenium: effects on a spatial discrimination reversal in adulthood.

Authors:  Miranda N Reed; Elliott M Paletz; M Christopher Newland
Journal:  Neurotoxicology       Date:  2006-04-15       Impact factor: 4.294

4.  Use of Central stonerollers (Cyprinidae: Campostoma anomalum) from Tennessee as a bioindicator of metal contamination.

Authors:  Joanna Burger; Kym Rouse Campbell; Todd S Campbell; Tara Shukla; Carline Dixon; Michael Gochfeld
Journal:  Environ Monit Assess       Date:  2005-11       Impact factor: 2.513

5.  Concentrations of mercury (Hg) and selenium (Se) in afterbirth and their relations with various factors.

Authors:  Danuta Kosik-Bogacka; Natalia Łanocha-Arendarczyk; Karolina Kot; Witold Malinowski; Sławomir Szymański; Olimpia Sipak-Szmigiel; Bogumiła Pilarczyk; Agnieszka Tomza-Marciniak; Joanna Podlasińska; Natalia Tomska; Żaneta Ciosek
Journal:  Environ Geochem Health       Date:  2018-02-28       Impact factor: 4.609

6.  Mercury and selenium levels in 19 species of saltwater fish from New Jersey as a function of species, size, and season.

Authors:  Joanna Burger; Michael Gochfeld
Journal:  Sci Total Environ       Date:  2011-02-02       Impact factor: 7.963

7.  Post-transcriptional defects of antioxidant selenoenzymes cause oxidative stress under methylmercury exposure.

Authors:  Fusako Usuki; Akio Yamashita; Masatake Fujimura
Journal:  J Biol Chem       Date:  2010-11-24       Impact factor: 5.157

8.  Seasonal, locational and size variations in mercury and selenium levels in striped bass (Morone saxatilis) from New Jersey.

Authors:  Michael Gochfeld; Joanna Burger; Christian Jeitner; Mark Donio; Taryn Pittfield
Journal:  Environ Res       Date:  2012-01-09       Impact factor: 6.498

9.  Mercury and selenium levels, and selenium:mercury molar ratios of brain, muscle and other tissues in bluefish (Pomatomus saltatrix) from New Jersey, USA.

Authors:  Joanna Burger; Christian Jeitner; Mark Donio; Taryn Pittfield; Michael Gochfeld
Journal:  Sci Total Environ       Date:  2012-11-30       Impact factor: 7.963

10.  Risk to consumers from mercury in bluefish (Pomatomus saltatrix) from New Jersey: Size, season and geographical effects.

Authors:  Joanna Burger
Journal:  Environ Res       Date:  2009-07-29       Impact factor: 6.498
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