Literature DB >> 3990686

Characterization and purification of lupus antigen La, and RNA-binding protein.

A M Francoeur, E K Chan, J I Garrels, M B Mathews.   

Abstract

HeLa cell La antigen, an RNA-binding protein, was characterized by using two-dimensional gel electrophoresis. Eight isoelectric forms (pI 6 to 7) were observed, many containing phosphate. An in vitro translation product similar in size and antigenicity was identified. The HeLa cell protein purified by using an assay based on ribonucleoprotein reconstitution with adenovirus VA RNAI also comprised several isoelectric forms.

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Year:  1985        PMID： 3990686      PMCID： PMC366753          DOI： 10.1128/mcb.5.3.586-590.1985

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  51 in total

1.  Quantitative film detection of 3H and 14C in polyacrylamide gels by fluorography.

Authors:  R A Laskey; A D Mills
Journal:  Eur J Biochem       Date:  1975-08-15

2.  High resolution two-dimensional electrophoresis of proteins.

Authors:  P H O'Farrell
Journal:  J Biol Chem       Date:  1975-05-25       Impact factor: 5.157

3.  Two dimensional gel electrophoresis and computer analysis of proteins synthesized by clonal cell lines.

Authors:  J I Garrels
Journal:  J Biol Chem       Date:  1979-08-25       Impact factor: 5.157

4.  Prolonged transcription in a cell-free system involving nuclei and cytoplasm.

Authors:  G J Wu; G Zubay
Journal:  Proc Natl Acad Sci U S A       Date:  1974-05       Impact factor: 11.205

5.  An efficient mRNA-dependent translation system from reticulocyte lysates.

Authors:  H R Pelham; R J Jackson
Journal:  Eur J Biochem       Date:  1976-08-01

6.  Purification of an acidic nuclear protein antigen and demonstration of its antibodies in subsets of patients with sicca syndrome.

Authors:  M Akizuki; M J Boehm-Truitt; S S Kassan; A D Steinberg; T M Chused
Journal:  J Immunol       Date:  1977-09       Impact factor: 5.422

7.  Mechanism for RNA splicing of gene transcripts.

Authors:  V Murray; R Holliday
Journal:  FEBS Lett       Date:  1979-10-01       Impact factor: 4.124

8.  Cell-free synthesis of adenovirus 2 proteins programmed by fractionated messenger RNA: a comparison of polypeptide products and messenger RNA lengths.

Authors:  C W Anderson; J B Lewis; J F Atkins; R F Gesteland
Journal:  Proc Natl Acad Sci U S A       Date:  1974-07       Impact factor: 11.205

9.  Faithful transcription of eukaryotic genes by RNA polymerase III in systems reconstituted with purified DNA templates.

Authors:  P A Weil; J Segall; B Harris; S Y Ng; R G Roeder
Journal:  J Biol Chem       Date:  1979-07-10       Impact factor: 5.157

10.  A soluble acidic protein of the cell nucleus which reacts with serum from patients with systemic lupus erythermatosus and Sjögren's syndrome.

Authors:  M Akizuki; R Powers; H R Holman
Journal:  J Clin Invest       Date:  1977-02       Impact factor: 14.808
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  18 in total

1.  Analysis of parotid glands of primary Sjögren's syndrome patients using proteomic technology reveals altered autoantigen composition and novel antigenic targets.

Authors:  E A Stea; J G Routsias; M Samiotaki; G Panayotou; E Papalambros; H M Moutsopoulos; A G Tzioufas
Journal:  Clin Exp Immunol       Date:  2007-01       Impact factor: 4.330

Review 2.  Structure and function of La and Ro RNPs.

Authors:  W J van Venrooij; R L Slobbe; G J Pruijn
Journal:  Mol Biol Rep       Date:  1993-08       Impact factor: 2.316

3.  The presence of an antigen reactive with a human autoantibody in Trichosia pubescens (Diptera: Sciaridae) and its association with certain transcriptionally active regions of the genome.

Authors:  J M Amabis; D C Amabis; J Kaburaki; B D Stollar
Journal:  Chromosoma       Date:  1990-04       Impact factor: 4.316

4.  Anti-SM and anti-U1-RNP lupus antibody fine specificities.

Authors:  A M Francoeur
Journal:  J Clin Immunol       Date:  1989-05       Impact factor: 8.317

5.  The small nuclear ribonucleoprotein SS-B/La binds RNA with a conserved protease-resistant domain of 28 kilodaltons.

Authors:  E K Chan; E M Tan
Journal:  Mol Cell Biol       Date:  1987-07       Impact factor: 4.272

6.  Lupus/Sjögren's autoantibody specificities in sera with paraproteins.

Authors:  A L Sestak; J B Harley; S Yoshida; M Reichlin
Journal:  J Clin Invest       Date:  1987-07       Impact factor: 14.808

7.  Phosphorylation of the Saccharomyces cerevisiae La protein does not appear to be required for its functions in tRNA maturation and nascent RNA stabilization.

Authors:  K S Long; T Cedervall; C Walch-Solimena; D A Noe; M J Huddleston; R S Annan; S L Wolin
Journal:  RNA       Date:  2001-11       Impact factor: 4.942

8.  Mosquito homolog of the La autoantigen binds to Sindbis virus RNA.

Authors:  N Pardigon; J H Strauss
Journal:  J Virol       Date:  1996-02       Impact factor: 5.103

9.  Eukaryotic transcription termination factor La mediates transcript release and facilitates reinitiation by RNA polymerase III.

Authors:  R J Maraia; D J Kenan; J D Keene
Journal:  Mol Cell Biol       Date:  1994-03       Impact factor: 4.272

Review 10.  Transcription termination by the eukaryotic RNA polymerase III.

Authors:  Aneeshkumar G Arimbasseri; Keshab Rijal; Richard J Maraia
Journal:  Biochim Biophys Acta       Date:  2012-10-23
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