Literature DB >> 3987501

Effect of acetazolamide (Diamox) on tear secretion.

E J van Agtmaal, L Thörig, N J van Haeringen.   

Abstract

The side effects of acetazolamide (Diamox) on lacrimation were measured in rats by means of the cotton-thread tear test. After a daily oral 1-mg dose (administered for five days), comparable to the dose used for adult humans on a drug-to-bodyweight basis, tear production remained unaffected but the lacrimal peroxidase secretion decreased by 60% of the baseline level. After withdrawal of acetazolamide the peroxidase secretion returned to the baseline level.

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Year:  1985        PMID: 3987501     DOI: 10.1007/bf00162013

Source DB:  PubMed          Journal:  Doc Ophthalmol        ISSN: 0012-4486            Impact factor:   2.379


  9 in total

1.  Intracellular distinction between peroxidase and catalase in exocrine cells of rat lacrimal gland: a biochemical and cytochemical study.

Authors:  V Herzog; H D Fahimi
Journal:  Histochemistry       Date:  1976-03-31

Review 2.  Site of action of diuretic drugs.

Authors:  J F Seely; J H Dirks
Journal:  Kidney Int       Date:  1977-01       Impact factor: 10.612

3.  The peroxidase-thiocyanate-hydrogenperoxide system in tear fluid and saliva of different species.

Authors:  N J van Haeringen; F T Ensink; E Glasius
Journal:  Exp Eye Res       Date:  1979-03       Impact factor: 3.467

4.  A new sensitive colorimetric assay for peroxidase using 3,3'-diaminobenzidine as hydrogen donor.

Authors:  V Herzog; H D Fahimi
Journal:  Anal Biochem       Date:  1973-10       Impact factor: 3.365

Review 5.  Clinical biochemistry of tears.

Authors:  N J Van Haeringen
Journal:  Surv Ophthalmol       Date:  1981 Sep-Oct       Impact factor: 6.048

6.  The fine-thread method: lacrimation test for measuring ocular side-effects of drugs in the rat.

Authors:  L Thörig; M Halperin; N J van Haeringen
Journal:  Doc Ophthalmol       Date:  1983-12-15       Impact factor: 2.379

7.  A modified Schirmer test: the fine-thread method for measuring lacrimation.

Authors:  K Kurihashi; N Yanagihara; Y Honda
Journal:  J Pediatr Ophthalmol       Date:  1977 Nov-Dec

8.  Cotton-thread tear test: an experimental study for testing drugs suspected of side effects on lacrimation.

Authors:  L Thörig; M Halperin; N J van Haeringen
Journal:  Doc Ophthalmol       Date:  1984-11-15       Impact factor: 2.379

9.  Comparison of enzymes of tears, lacrimal gland fluid and lacrimal gland tissue in the rat.

Authors:  L Thörig; N J van Haeringen; G Wijngaards
Journal:  Exp Eye Res       Date:  1984-06       Impact factor: 3.467

  9 in total
  2 in total

1.  Carbonic anhydrase isozyme VI in rat lacrimal gland.

Authors:  Y Ogawa; S Toyosawa; T Inagaki; S S Hong; N Ijuhin
Journal:  Histochem Cell Biol       Date:  1995-05       Impact factor: 4.304

2.  The presence of carbonic anhydrase in orbital glands. An enzyme-histochemical study in cynomolgus monkeys and rabbits.

Authors:  M Eichhorn
Journal:  Histochemistry       Date:  1988
  2 in total

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