Literature DB >> 6662007

The fine-thread method: lacrimation test for measuring ocular side-effects of drugs in the rat.

L Thörig, M Halperin, N J van Haeringen.   

Abstract

Tear production was measured by means of the fine-cotton-thread method in rats. Sedation with hypnorm had no pharmacological effect on normal tear production. Daily oral administration of atropine which was comparable with the dose used for human adults on a drug-to-weight basis, resulted in a 60-percent reduction of tearing. Tearing returned to base-line levels after withdrawal of atropine.

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Year:  1983        PMID： 6662007     DOI： 10.1007/bf00154706

Source DB:  PubMed          Journal:  Doc Ophthalmol        ISSN： 0012-4486            Impact factor:   2.379


  7 in total

1.  The peroxidase-thiocyanate-hydrogenperoxide system in tear fluid and saliva of different species.

Authors:  N J van Haeringen; F T Ensink; E Glasius
Journal:  Exp Eye Res       Date:  1979-03       Impact factor: 3.467

2.  Basic lacrimal secretion test.

Authors:  K Singh; I S Jain
Journal:  Ophthalmologica       Date:  1973       Impact factor: 3.250

3.  [Mogadon, aspirin and lacrimal secretion].

Authors:  M Carreras y Matas
Journal:  Rev Esp Otoneurooftalmol Neurocir       Date:  1973 Jul-Aug

4.  Effect of atropine on tear formation in anesthetized dogs.

Authors:  J W Ludders; J E Heavner
Journal:  J Am Vet Med Assoc       Date:  1979-09-15       Impact factor: 1.936

5.  Evaluation of tear formation in the dog, using a modification of the Schirmer tear test.

Authors:  K N Gelatt; R L Peiffer; J L Erickson; G G Gum
Journal:  J Am Vet Med Assoc       Date:  1975-02-15       Impact factor: 1.936

6.  Decreased tear production associated with general anesthesia in the dog.

Authors:  W A Vestre; A H Brightman; L C Helper; J C Lowery
Journal:  J Am Vet Med Assoc       Date:  1979-05-01       Impact factor: 1.936

7.  A modified Schirmer test: the fine-thread method for measuring lacrimation.

Authors:  K Kurihashi; N Yanagihara; Y Honda
Journal:  J Pediatr Ophthalmol       Date:  1977 Nov-Dec
  7 in total
  3 in total

Review 1.  Ocular toxicity of systemic asthma and allergy treatments.

Authors:  Leonard Bielory
Journal:  Curr Allergy Asthma Rep       Date:  2006-07       Impact factor: 4.806

2.  Effect of acetazolamide (Diamox) on tear secretion.

Authors:  E J van Agtmaal; L Thörig; N J van Haeringen
Journal:  Doc Ophthalmol       Date:  1985-01-31       Impact factor: 2.379

3.  Cotton-thread tear test: an experimental study for testing drugs suspected of side effects on lacrimation.

Authors:  L Thörig; M Halperin; N J van Haeringen
Journal:  Doc Ophthalmol       Date:  1984-11-15       Impact factor: 2.379
  3 in total

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