Literature DB >> 3953578

Aldehyde dehydrogenase polymorphism in North American, South American, and Mexican Indian populations.

H W Goedde, D P Agarwal, S Harada, F Rothhammer, J O Whittaker, R Lisker.   

Abstract

While about 40% of the South American Indian populations (Atacameños, Mapuche, Shuara) were found to be deficient in aldehyde dehydrogenase isozyme I (ALDH2 or E2), preliminary investigations showed very low incidence of isozyme deficiency among North American natives (Sioux, Navajo) and Mexican Indians (mestizo). Possible implications of such trait differences on cross-cultural behavioral response to alcohol drinking are discussed.

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Year:  1986        PMID： 3953578      PMCID： PMC1684787     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN： 0002-9297            Impact factor:   11.025


  19 in total

1.  Metabolic responses of Chinese, Japanese and Europeans to alcohol.

Authors:  J M Hanna
Journal:  Alcohol Clin Exp Res       Date:  1978-01       Impact factor: 3.455

2.  Possible protective role against alcoholism for aldehyde dehydrogenase isozyme deficiency in Japan.

Authors:  S Harada; D P Agarwal; H W Goedde; S Tagaki; B Ishikawa
Journal:  Lancet       Date:  1982-10-09       Impact factor: 79.321

3.  Aldehyde dehydrogenase deficiency as cause of facial flushing reaction to alcohol in Japanese.

Authors:  S Harada; D P Agarwal; H W Goedde
Journal:  Lancet       Date:  1981-10-31       Impact factor: 79.321

4.  Racial differences in alcohol sensitivity: a new hypothesis.

Authors:  H W Goedde; S Harada; D P Agarwal
Journal:  Hum Genet       Date:  1979-10-02       Impact factor: 4.132

5.  Population genetic studies on aldehyde dehydrogenase isozyme deficiency and alcohol sensitivity.

Authors:  H W Goedde; D P Agarwal; S Harada; D Meier-Tackmann; D Ruofu; U Bienzle; A Kroeger; L Hussein
Journal:  Am J Hum Genet       Date:  1983-07       Impact factor: 11.025

6.  Liver alcohol dehydrogenase and aldehyde dehydrogenase in the Japanese: isozyme variation and its possible role in alcohol intoxication.

Authors:  S Harada; S Misawa; D P Agarwal; H W Goedde
Journal:  Am J Hum Genet       Date:  1980-01       Impact factor: 11.025

7.  Racial differences in biological sensitivity to ethanol: the role of alcohol dehydrogenase and aldehyde dehydrogenase isozymes.

Authors:  D P Agarwal; S Harada; H W Goedde
Journal:  Alcohol Clin Exp Res       Date:  1981-01       Impact factor: 3.455

8.  Ethnic differences in alcohol sensitivity.

Authors:  P H Wolff
Journal:  Science       Date:  1972-01-28       Impact factor: 47.728

9.  Population genetic and family studies on aldehyde dehydrogenase deficiency and alcohol sensitivity.

Authors:  H W Goedde; D P Agarwal; R Eckey; S Harada
Journal:  Alcohol       Date:  1985 May-Jun       Impact factor: 2.405

10.  Genetic studies on alcohol-metabolizing enzymes: detection of isozymes in human hair roots.

Authors:  H W Goedde; D P Agarwal; S Harada
Journal:  Enzyme       Date:  1980
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  13 in total

Review 1.  Gene frequencies of alcohol dehydrogenase2 and aldehyde dehydrogenase2 in Northwest Coast Amerindians.

Authors:  S H Chen; M Zhang; C R Scott
Journal:  Hum Genet       Date:  1992-05       Impact factor: 4.132

2.  Distribution of ADH2 and ALDH2 genotypes in different populations.

Authors:  H W Goedde; D P Agarwal; G Fritze; D Meier-Tackmann; S Singh; G Beckmann; K Bhatia; L Z Chen; B Fang; R Lisker
Journal:  Hum Genet       Date:  1992-01       Impact factor: 4.132

3.  Genotypes for aldehyde dehydrogenase deficiency and alcohol sensitivity. The inactive ALDH2(2) allele is dominant.

Authors:  D W Crabb; H J Edenberg; W F Bosron; T K Li
Journal:  J Clin Invest       Date:  1989-01       Impact factor: 14.808

4.  Inheritance of mitochondrial aldehyde dehydrogenase: genotyping in Chinese, Japanese and South Korean families reveals dominance of the mutant allele.

Authors:  S Singh; G Fritze; B L Fang; S Harada; Y K Paik; R Eckey; D P Agarwal; H W Goedde
Journal:  Hum Genet       Date:  1989-09       Impact factor: 4.132

5.  Detection and partial characterization of a variant form of cytosolic aldehyde dehydrogenase isozyme.

Authors:  R Eckey; D P Agarwal; N Saha; H W Goedde
Journal:  Hum Genet       Date:  1986-01       Impact factor: 4.132

6.  SSCP primer design based on single-strand DNA structure predicted by a DNA folding program.

Authors:  D A Nielsen; A Novoradovsky; D Goldman
Journal:  Nucleic Acids Res       Date:  1995-06-25       Impact factor: 16.971

7.  Species and inter-individual differences in metabolic capacity of di(2-ethylhexyl)phthalate (DEHP) between human and mouse livers.

Authors:  Yuki Ito; Michihiro Kamijima; Chie Hasegawa; Masahiro Tagawa; Toshio Kawai; Mio Miyake; Yumi Hayashi; Hisao Naito; Tamie Nakajima
Journal:  Environ Health Prev Med       Date:  2013-09-28       Impact factor: 3.674

Review 8.  A personalized medicine approach for Asian Americans with the aldehyde dehydrogenase 2*2 variant.

Authors:  Eric R Gross; Vanessa O Zambelli; Bryce A Small; Julio C B Ferreira; Che-Hong Chen; Daria Mochly-Rosen
Journal:  Annu Rev Pharmacol Toxicol       Date:  2014-09-29       Impact factor: 13.820

9.  Genotyping of mitochondrial aldehyde dehydrogenase in blood samples using allele-specific oligonucleotides: comparison with phenotyping in hair roots.

Authors:  H W Goedde; S Singh; D P Agarwal; G Fritze; K Stapel; Y K Paik
Journal:  Hum Genet       Date:  1989-03       Impact factor: 4.132

10.  Statistical analysis of the associations between polymorphisms within aldehyde dehydrogenase 2 (ALDH2), and quantitative and qualitative traits extracted from a large-scale database of Japanese single-nucleotide polymorphisms (SNPs).

Authors:  Junichiro Nose; Akira Saito; Naoyuki Kamatani
Journal:  J Hum Genet       Date:  2008-03-04       Impact factor: 3.172
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