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Literature DB >> 6881146

Population genetic studies on aldehyde dehydrogenase isozyme deficiency and alcohol sensitivity.

H W Goedde, D P Agarwal, S Harada, D Meier-Tackmann, D Ruofu, U Bienzle, A Kroeger, L Hussein.

Abstract

Population genetic studies on aldehyde dehydrogenase polymorphism using hair-root samples were performed on Europeans, Liberians, Sudanese, Egyptians, Kenyans, Vietnamese, Japanese, Indonesians, Chinese, Thais, and South American Indians. A possible correlation between ALDH I deficiency and sensitivity to alcohol in Oriental populations is discussed.

Entities: Chemical Disease

Mesh：

Substances：

Year: 1983 PMID： 6881146 PMCID： PMC1685745

Source DB: PubMed Journal: Am J Hum Genet ISSN： 0002-9297 Impact factor: 11.025

8 in total

1. Aldehyde dehydrogenase deficiency as cause of facial flushing reaction to alcohol in Japanese.

Authors: S Harada; D P Agarwal; H W Goedde
Journal: Lancet Date: 1981-10-31 Impact factor: 79.321

2. Racial differences in alcohol sensitivity: a new hypothesis.

Authors: H W Goedde; S Harada; D P Agarwal
Journal: Hum Genet Date: 1979-10-02 Impact factor: 4.132

3. Liver alcohol dehydrogenase and aldehyde dehydrogenase in the Japanese: isozyme variation and its possible role in alcohol intoxication.

Authors: S Harada; S Misawa; D P Agarwal; H W Goedde
Journal: Am J Hum Genet Date: 1980-01 Impact factor: 11.025

4. Electrophoretic and biochemical studies of human aldehyde dehydrogenase isozymes in various tissues.

Authors: S Harada; D P Agarwal; H W Goedde
Journal: Life Sci Date: 1980-05-26 Impact factor: 5.037

5. Two aldehyde dehydrogenases from human liver. Isolation via affinity chromatography and characterization of the isozymes.

Authors: N J Greenfield; R Pietruszko
Journal: Biochim Biophys Acta Date: 1977-07-08

6. Alcohol metabolizing enzymes: studies of isozymes in human biopsies and cultured fibroblasts.

Authors: H W Goedde; D P Agarwal; S Harada
Journal: Clin Genet Date: 1979-07 Impact factor: 4.438

7. Genetic studies on alcohol-metabolizing enzymes: detection of isozymes in human hair roots.

Authors: H W Goedde; D P Agarwal; S Harada
Journal: Enzyme Date: 1980

8. Human liver aldehyde dehydrogenase in Chinese and Asiatic Indians: gene deletion and its possible implications in alcohol metabolism.

Authors: Y S Teng
Journal: Biochem Genet Date: 1981-02 Impact factor: 1.890

8 in total

30 in total

1. Trans-ancestry mutational landscape of hepatocellular carcinoma genomes.

Authors: Yasushi Totoki; Kenji Tatsuno; Kyle R Covington; Hiroki Ueda; Chad J Creighton; Mamoru Kato; Shingo Tsuji; Lawrence A Donehower; Betty L Slagle; Hiromi Nakamura; Shogo Yamamoto; Eve Shinbrot; Natsuko Hama; Megan Lehmkuhl; Fumie Hosoda; Yasuhito Arai; Kim Walker; Mahmoud Dahdouli; Kengo Gotoh; Genta Nagae; Marie-Claude Gingras; Donna M Muzny; Hidenori Ojima; Kazuaki Shimada; Yutaka Midorikawa; John A Goss; Ronald Cotton; Akimasa Hayashi; Junji Shibahara; Shumpei Ishikawa; Jacfranz Guiteau; Mariko Tanaka; Tomoko Urushidate; Shoko Ohashi; Naoko Okada; Harsha Doddapaneni; Min Wang; Yiming Zhu; Huyen Dinh; Takuji Okusaka; Norihiro Kokudo; Tomoo Kosuge; Tadatoshi Takayama; Masashi Fukayama; Richard A Gibbs; David A Wheeler; Hiroyuki Aburatani; Tatsuhiro Shibata
Journal: Nat Genet Date: 2014-11-02 Impact factor: 38.330

2. The aldehyde dehydrogenase ALDH22 allele exhibits dominance over ALDH21 in transduced HeLa cells.

Authors: Q Xiao; H Weiner; T Johnston; D W Crabb
Journal: J Clin Invest Date: 1995-11 Impact factor: 14.808

3. Effects of H2-receptor antagonists on ethanol metabolism in Japanese volunteers.

Authors: E Tanaka; K Nakamura
Journal: Br J Clin Pharmacol Date: 1988-07 Impact factor: 4.335

4. The mutation in the mitochondrial aldehyde dehydrogenase (ALDH2) gene responsible for alcohol-induced flushing increases turnover of the enzyme tetramers in a dominant fashion.

Authors: Q Xiao; H Weiner; D W Crabb
Journal: J Clin Invest Date: 1996-11-01 Impact factor: 14.808

5. Inheritance of mitochondrial aldehyde dehydrogenase: genotyping in Chinese, Japanese and South Korean families reveals dominance of the mutant allele.

Authors: S Singh; G Fritze; B L Fang; S Harada; Y K Paik; R Eckey; D P Agarwal; H W Goedde
Journal: Hum Genet Date: 1989-09 Impact factor: 4.132

6. Genotyping of mitochondrial aldehyde dehydrogenase in blood samples using allele-specific oligonucleotides: comparison with phenotyping in hair roots.

Authors: H W Goedde; S Singh; D P Agarwal; G Fritze; K Stapel; Y K Paik
Journal: Hum Genet Date: 1989-03 Impact factor: 4.132

7. Research on alcohol metabolism among Asians and its implications for understanding causes of alcoholism.

Authors: R F Suddendorf
Journal: Public Health Rep Date: 1989 Nov-Dec Impact factor: 2.792

Review 8. Aldehyde dehydrogenase 2 in cardiac protection: a new therapeutic target?

Authors: Grant R Budas; Marie-Hélène Disatnik; Daria Mochly-Rosen
Journal: Trends Cardiovasc Med Date: 2009-07 Impact factor: 6.677

9. Genotypes of alcohol-metabolizing enzymes in Japanese with alcohol liver diseases: a strong association of the usual Caucasian-type aldehyde dehydrogenase gene (ALDH1(2)) with the disease.

Authors: A Shibuya; A Yoshida
Journal: Am J Hum Genet Date: 1988-11 Impact factor: 11.025

10. Characterization of the East Asian variant of aldehyde dehydrogenase-2: bioactivation of nitroglycerin and effects of Alda-1.

Authors: Matteo Beretta; Antonius C F Gorren; M Verena Wenzl; Robert Weis; Michael Russwurm; Doris Koesling; Kurt Schmidt; Bernd Mayer
Journal: J Biol Chem Date: 2009-11-11 Impact factor: 5.157