Literature DB >> 3943602

Regression of genetically determined polycystic kidney disease in murine organ culture.

E D Avner, W E Sweeney, N P Piesco, D Ellis.   

Abstract

Cystic kidneys from the mutant CPK strain of C57BL/6J mice were cultured in serum-free organ culture. During 120 h of incubation in chemically-defined medium, CPK cystic tubular changes underwent complete regression. Environmental factors regulate the expression of genetically determined polycystic kidney disease in this model.

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Year:  1986        PMID： 3943602     DOI： 10.1007/bf01975904

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  10 in total

1.  Cortisone-induced renal changes in the rabbit: a microdissection study.

Authors:  T J BAXTER
Journal:  Br J Exp Pathol       Date:  1960-04

2.  Cystic diseases of the kidney in children.

Authors:  S K Anand; U Alon; J C Chan
Journal:  Adv Pediatr       Date:  1984

3.  Development of the embryonic murine kidney in normal and congenital polycystic kidney disease: characterization of a proximal tubular degenerative process as the first observable light microscopic defect.

Authors:  R Nidess; W E Koch; F A Fried; E McFarland; J Mandell
Journal:  J Urol       Date:  1984-01       Impact factor: 7.450

4.  Cyst formation in metanephric organ culture induced by cis-dichlorodiammineplatinum (II).

Authors:  E D Avner; W E Sweeney; D Ellis
Journal:  Experientia       Date:  1983-01-15

5.  A new model of glucocorticoid-induced metanephric maldevelopment.

Authors:  E D Avner; W E Sweeney; N P Piesco; D Ellis
Journal:  Experientia       Date:  1984-05-15

6.  Murine congenital polycystic kidney disease: a model for studying development of cystic disease.

Authors:  G M Preminger; W E Koch; F A Fried; E McFarland; E D Murphy; J Mandell
Journal:  J Urol       Date:  1982-03       Impact factor: 7.450

7.  Metanephric development in serum-free organ culture.

Authors:  E D Avner; D Ellis; T Temple; R Jaffe
Journal:  In Vitro       Date:  1982-08

8.  Polycystic renal disease: a new experimental model.

Authors:  D Y Perey; R C Herdman; R A Good
Journal:  Science       Date:  1967-10-27       Impact factor: 47.728

9.  Hydrocortisone-induced cystic metanephric maldevelopment in serum-free organ culture.

Authors:  E D Avner; N P Piesco; W E Sweeney; F M Studnicki; G H Fetterman; D Ellis
Journal:  Lab Invest       Date:  1984-02       Impact factor: 5.662

10.  Reversible changes of tubular cell and basement membrane in drug-induced renal cystic disease.

Authors:  Y S Kanwar; F A Carone
Journal:  Kidney Int       Date:  1984-07       Impact factor: 10.612
  10 in total
  2 in total

1.  Renal and biliary abnormalities in a new murine model of autosomal recessive polycystic kidney disease.

Authors:  J Nauta; Y Ozawa; W E Sweeney; J C Rutledge; E D Avner
Journal:  Pediatr Nephrol       Date:  1993-04       Impact factor: 3.714

2.  Congenital murine polycystic kidney disease. I. The ontogeny of tubular cyst formation.

Authors:  E D Avner; F E Studnicki; M C Young; W E Sweeney; N P Piesco; D Ellis; G H Fettermann
Journal:  Pediatr Nephrol       Date:  1987-10       Impact factor: 3.714
  2 in total

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