Literature DB >> 6723915

A new model of glucocorticoid-induced metanephric maldevelopment.

E D Avner, W E Sweeney, N P Piesco, D Ellis.   

Abstract

A new experimental model of glucocorticoid-induced tubular cyst formation has been developed in metanephric organ culture. The addition of cortisol (1.4 X 10(-5) M) to chemically defined serum-free culture medium produces cystic changes during in vitro nephrogenesis . The model isolates the role of glucocorticoids in experimental cyst formation.

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Year:  1984        PMID： 6723915     DOI： 10.1007/BF01952400

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  6 in total

1.  CARDIORENAL LESIONS OF POTASSIUM DEPLETION OR STEROID THERAPY IN THE RAT.

Authors:  P M NEWBERNE
Journal:  Am J Vet Res       Date:  1964-07       Impact factor: 1.156

2.  Cortisone-induced renal changes in the rabbit: a microdissection study.

Authors:  T J BAXTER
Journal:  Br J Exp Pathol       Date:  1960-04

3.  Glucocorticoids selectively decrease the synthesis of hydroxylated collagen peptides.

Authors:  R A Newman; K R Cutroneo
Journal:  Mol Pharmacol       Date:  1978-01       Impact factor: 4.436

4.  Metanephric development in serum-free organ culture.

Authors:  E D Avner; D Ellis; T Temple; R Jaffe
Journal:  In Vitro       Date:  1982-08

5.  Polycystic renal disease: a new experimental model.

Authors:  D Y Perey; R C Herdman; R A Good
Journal:  Science       Date:  1967-10-27       Impact factor: 47.728

6.  Adrenal corticosteroid-induced renal cystic disease in the newborn hamster.

Authors:  R B Filmer; F A Carone; R G Rowland; J R Babcock
Journal:  Am J Pathol       Date:  1973-09       Impact factor: 4.307
  6 in total
  3 in total

Review 1.  Renal epithelial development in organotypic culture.

Authors:  E D Avner; N P Piesco; W E Sweeney; D Ellis
Journal:  Pediatr Nephrol       Date:  1988-01       Impact factor: 3.714

2.  Growth factor requirements of organogenesis in serum-free metanephric organ culture.

Authors:  E D Avner; W E Sweeney; N P Piesco; D Ellis
Journal:  In Vitro Cell Dev Biol       Date:  1985-05

3.  Regression of genetically determined polycystic kidney disease in murine organ culture.

Authors:  E D Avner; W E Sweeney; N P Piesco; D Ellis
Journal:  Experientia       Date:  1986-01-15
  3 in total

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