Literature DB >> 6681778

Cyst formation in metanephric organ culture induced by cis-dichlorodiammineplatinum (II).

E D Avner, W E Sweeney, D Ellis.   

Abstract

A new experimental model of renal tubular cyst formation has been developed in metanephric organ culture. The addition of cis-dichlorodiammineplatinum (II), 50 micrograms/ml, to culture medium induces cystic changes during in vitro nephrogenesis. The model has particular utility in the study of basic mechanisms underlying renal tubular cystic changes, as well as the mechanisms by which nephrotoxins may mediate renal tubular injury.

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Year:  1983        PMID： 6681778     DOI： 10.1007/bf01960636

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  8 in total

1.  The pathogenesis of drug-induced renal cystic disease.

Authors:  F A Carone; R G Rowland; S G Perlman; C E Ganote
Journal:  Kidney Int       Date:  1974-06       Impact factor: 10.612

2.  Cystic changes in fetal kidneys following ureteral ligation: studies by microdissection.

Authors:  G H Fetterman; M M Ravitch; F E Sherman
Journal:  Kidney Int       Date:  1974-02       Impact factor: 10.612

3.  Cystic disease of the kidney in the newborn infant.

Authors:  J Resnick; R L Vernier
Journal:  Clin Perinatol       Date:  1981-06       Impact factor: 3.430

4.  Metanephric development in serum-free organ culture.

Authors:  E D Avner; D Ellis; T Temple; R Jaffe
Journal:  In Vitro       Date:  1982-08

5.  Nephron obstruction in nordihydroguaiaretic acid-induced renal cystic disease.

Authors:  A P Evan; K D Gardner
Journal:  Kidney Int       Date:  1979-01       Impact factor: 10.612

6.  Cyst formation in rat kidney induced by cis-platinum administration.

Authors:  D C Dobyan; D Hill; T Lewis; R E Bulger
Journal:  Lab Invest       Date:  1981-09       Impact factor: 5.662

7.  Acute and chronic cisplatin nephropathy in rats.

Authors:  D D Choie; D S Longnecker; A A del Campo
Journal:  Lab Invest       Date:  1981-05       Impact factor: 5.662

Review 8.  Renal and electrolyte disturbances associated with cisplatin.

Authors:  J D Blachley; J B Hill
Journal:  Ann Intern Med       Date:  1981-11       Impact factor: 25.391
  8 in total
  4 in total

1.  Growth factor requirements of organogenesis in serum-free metanephric organ culture.

Authors:  E D Avner; W E Sweeney; N P Piesco; D Ellis
Journal:  In Vitro Cell Dev Biol       Date:  1985-05

2.  Long-term studies of cisplatin-induced reductions in porcine renal functional reserve.

Authors:  M E Robbins; T B Bywaters; R S Jaenke; J W Hopewell; L M Matheson; P Tothill; E Whitehouse
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333

3.  Regression of genetically determined polycystic kidney disease in murine organ culture.

Authors:  E D Avner; W E Sweeney; N P Piesco; D Ellis
Journal:  Experientia       Date:  1986-01-15

4.  Tubular dilatation in the repair process of ischaemic tubular necrosis.

Authors:  A Shimizu; Y Masuda; M Ishizaki; Y Sugisaki; N Yamanaka
Journal:  Virchows Arch       Date:  1994       Impact factor: 4.064
  4 in total

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