Literature DB >> 3943072

Centromere spreading in a case of megaloblastic anemia "cured" under TC 199 culture conditions.

R Bamezai, Y Shiraishi, H Taguchi.   

Abstract

The present study discusses the possible reasons of appearance and disappearance of centromere spreading in chromosomes obtained from bone marrow cultures in RPMI 1640 and TC 199 media, respectively, in a case of megaloblastic anemia. This prevention or curing effect of centromeric region is suggested to have occurred due to exogenous thymidine present in TC 199 medium, probably reflecting the failure of proper DNA synthesis.

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Year:  1986        PMID: 3943072     DOI: 10.1016/0165-4608(86)90093-2

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN: 0165-4608


  3 in total

1.  Mitotic disturbance associated with mosaic aneuploidies.

Authors:  K Miller; W Müller; L Winkler; M R Hadam; J H Ehrich; S D Flatz
Journal:  Hum Genet       Date:  1990-03       Impact factor: 4.132

2.  Chromosome abnormalities in tuberous sclerosis.

Authors:  S Scappaticci; D Cerimele; M Tondi; R Vivarelli; A Fois; M Fraccaro
Journal:  Hum Genet       Date:  1988-06       Impact factor: 4.132

3.  Centromere splitting in bladder cancer.

Authors:  G Berrozpe; M R Caballin; R Miró; A Gelabert; J Egozcue
Journal:  Hum Genet       Date:  1990-07       Impact factor: 4.132

  3 in total

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