Literature DB >> 2370046

Centromere splitting in bladder cancer.

G Berrozpe1, M R Caballin, R Miró, A Gelabert, J Egozcue.   

Abstract

Cytogenetic studies on a bladder carcinoma, carried out using short time cultures, showed centromere splitting (CS) mainly affecting chromosomes 22, 13, 14, 21, 15, 20, 12, 7, 17, and 18. Clonal trisomies and monosomies were also detected. Our case is the first description of CS in bladder tumor cells. Our results suggest that CS is an early phenomenon in the karyotypic evolution of this case; it can be considered a primary, yet unspecific, chromosome change related to aneuploidy in bladder cancer.

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Year:  1990        PMID： 2370046     DOI： 10.1007/bf00193193

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  26 in total

1.  Rhabdomyosarcoma in Roberts syndrome.

Authors:  S L Wenger; J Blatt; M W Steele; D A Lloyd; M Bellinger; C K Phebus; M Horn; R Jaffe
Journal:  Cancer Genet Cytogenet       Date:  1988-04

2.  Sequence of centromere separation: multicentric chromosomes, repetitive DNA and aneuploidy.

Authors:  B K Vig
Journal:  Prog Clin Biol Res       Date:  1986

3.  A sibship with the pseudothalidomide syndrome and an association with Rh incompatibility.

Authors:  C Judge
Journal:  Med J Aust       Date:  1973-08-11       Impact factor: 7.738

4.  Roberts's syndrome. II. Aberrant Y-chromosome behavior.

Authors:  E Louie; J German
Journal:  Clin Genet       Date:  1981-01       Impact factor: 4.438

5.  A mechanism of x chromosome aneuploidy in lymphocytes of aging women.

Authors:  P H Fitzgerald
Journal:  Humangenetik       Date:  1975-06-19

6.  Out-of-phase separation of a G-group chromosome in a woman with chronic myelogenous leukemia.

Authors:  B K Vig
Journal:  Cancer Genet Cytogenet       Date:  1984-06

7.  A possible specific chromosome change in transitional cell carcinoma of the bladder.

Authors:  Z Gibas; G R Prout; J E Pontes; J G Connolly; A A Sandberg
Journal:  Cancer Genet Cytogenet       Date:  1986-01-15

8.  Cytogenetic investigation on 30 bladder carcinomas.

Authors:  R Vanni; R M Scarpa; M Nieddu; E Usai
Journal:  Cancer Genet Cytogenet       Date:  1988-01

9.  Evidence for the repeated primary non-disjunction of chromosome 21 as a result of premature centromere division (PCD).

Authors:  P H Fitzgerald; S A Archer; C M Morris
Journal:  Hum Genet       Date:  1986-01       Impact factor: 4.132

Review 10.  Sequence of centromere separation: occurrence, possible significance, and control.

Authors:  B K Vig
Journal:  Cancer Genet Cytogenet       Date:  1983-03
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