Literature DB >> 3935235

Improved survival of patients with homozygous familial hypercholesterolaemia treated with plasma exchange.

G R Thompson, J P Miller, J L Breslow.   

Abstract

Plasma exchange was undertaken in five patients with homozygous familial hypercholesterolaemia at intervals of two weeks for a mean of 8.4 years. These patients had survived an average of 5.5 years longer than their five respective homozygous siblings (p = 0.3), each of whom must have had a matching genetic defect but who died untreated. The 37% decrease in peak serum cholesterol concentrations maintained by plasma exchange presumably reduced progression of atherosclerosis in the treated patients and thus lessened their risk of premature death.

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Year:  1985        PMID： 3935235      PMCID： PMC1418783          DOI： 10.1136/bmj.291.6510.1671

Source DB:  PubMed          Journal:  Br Med J (Clin Res Ed)        ISSN： 0267-0623


  31 in total

1.  Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge.

Authors:  W T Friedewald; R I Levy; D S Fredrickson
Journal:  Clin Chem       Date:  1972-06       Impact factor: 8.327

2.  Risks of ischaemic heart-disease in familial hyperlipoproteinaemic states.

Authors:  J Slack
Journal:  Lancet       Date:  1969-12-27       Impact factor: 79.321

3.  The LDL receptor locus in familial hypercholesterolemia: multiple mutations disrupt transport and processing of a membrane receptor.

Authors:  H Tolleshaug; K K Hobgood; M S Brown; J L Goldstein
Journal:  Cell       Date:  1983-03       Impact factor: 41.582

4.  Cholesterol-lowering effect of mevinolin, an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme a reductase, in healthy volunteers.

Authors:  J A Tobert; G D Bell; J Birtwell; I James; W R Kukovetz; J S Pryor; A Buntinx; I B Holmes; Y S Chao; J A Bolognese
Journal:  J Clin Invest       Date:  1982-04       Impact factor: 14.808

5.  Heart-liver transplantation in a patient with familial hypercholesterolaemia.

Authors:  T E Starzl; D W Bilheimer; H T Bahnson; B W Shaw; R L Hardesty; B P Griffith; S Iwatsuki; B J Zitelli; J C Gartner; J J Malatack
Journal:  Lancet       Date:  1984-06-23       Impact factor: 79.321

6.  Familial hypercholesterolemia: identification of a defect in the regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity associated with overproduction of cholesterol.

Authors:  J L Goldstein; M S Brown
Journal:  Proc Natl Acad Sci U S A       Date:  1973-10       Impact factor: 11.205

7.  The human LDL receptor: a cysteine-rich protein with multiple Alu sequences in its mRNA.

Authors:  T Yamamoto; C G Davis; M S Brown; W J Schneider; M L Casey; J L Goldstein; D W Russell
Journal:  Cell       Date:  1984-11       Impact factor: 41.582

8.  The association of LDL receptor activity, LDL cholesterol level, and clinical course in homozygous familial hypercholesterolemia.

Authors:  D L Sprecher; J M Hoeg; E J Schaefer; L A Zech; R E Gregg; E Lakatos; H B Brewer
Journal:  Metabolism       Date:  1985-03       Impact factor: 8.694

9.  Cardiovascular features of homozygous familial hypercholesterolemia: analysis of 16 patients.

Authors:  D L Sprecher; E J Schaefer; K M Kent; R E Gregg; L A Zech; J M Hoeg; B McManus; W C Roberts; H B Brewer
Journal:  Am J Cardiol       Date:  1984-07-01       Impact factor: 2.778

10.  Liver transplantation to provide low-density-lipoprotein receptors and lower plasma cholesterol in a child with homozygous familial hypercholesterolemia.

Authors:  D W Bilheimer; J L Goldstein; S M Grundy; T E Starzl; M S Brown
Journal:  N Engl J Med       Date:  1984-12-27       Impact factor: 91.245
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  27 in total

1.  Long-term efficacy of low-density lipoprotein apheresis for focal and segmental glomerulosclerosis.

Authors:  Yukihiko Kawasaki; Sigeo Suzuki; Ayumi Matsumoto; Kei Takano; Kazuhide Suyama; Koichi Hashimoto; Junzo Suzuki; Hitoshi Suzuki; Mitsuaki Hosoya
Journal:  Pediatr Nephrol       Date:  2007-02-03       Impact factor: 3.714

2.  Aortic stenosis in homozygous familial hypercholesterolaemia.

Authors:  L Rallidis; P Nihoyannopoulos; G R Thompson
Journal:  Heart       Date:  1996-07       Impact factor: 5.994

Review 3.  Familial hypercholesterolemia: developments in diagnosis and treatment.

Authors:  Gerald Klose; Ulrich Laufs; Winfried März; Eberhard Windler
Journal:  Dtsch Arztebl Int       Date:  2014-08-04       Impact factor: 5.594

4.  The Italian Consensus Conferences on low density lipoprotein-cholesterol apheresis.

Authors:  Anja Vogt
Journal:  Blood Transfus       Date:  2016-07-07       Impact factor: 3.443

Review 5.  Clinical consequences of hyperlipidaemia.

Authors:  G R Thompson
Journal:  J Inherit Metab Dis       Date:  1988       Impact factor: 4.982

Review 6.  Dietary fat and coronary heart disease.

Authors:  M F Oliver
Journal:  Br Heart J       Date:  1987-11

Review 7.  The role of microsomal triglyceride transfer protein inhibitors in the treatment of patients with familial hypercholesterolemia: risks, benefits, and management.

Authors:  Zahid Ahmad; Amit Khera
Journal:  Curr Atheroscler Rep       Date:  2015-01       Impact factor: 5.113

Review 8.  [Pathophysiology and therapy of lipid metabolism disorders in kidney diseases].

Authors:  C J Olbricht
Journal:  Klin Wochenschr       Date:  1991-08-01

9.  Low-density lipoprotein apheresis: an evidence-based analysis.

Authors: 
Journal:  Ont Health Technol Assess Ser       Date:  2006-11-01

10.  Changes of atherosclerosis of the carotid arteries due to severe familial hypercholesterolemia following long-term plasmapheresis, assessed by duplex scan.

Authors:  C Keller; F A Spengel
Journal:  Klin Wochenschr       Date:  1988-02-15
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