Literature DB >> 3923926

Mechanism of action of aflatoxin B1 in Bacillus megaterium.

R P Tiwari, C K Dham, T C Bhalla, S S Saini, D V Vadehra.   

Abstract

Bacillus megaterium cells from various growth phases were equally susceptible to the lethal effects of aflatoxin B1. Known surfactants (EDTA and Tween-80) accentuated the effects of aflatoxin B1. Viability and inulin uptake in aflatoxin B1-exposed cells decreased considerably. The effect was concentration dependent. A straight-line relationship observed in the death curve indicated a single target for aflatoxin B1 action in B. megaterium. Leakage of intracellular constituents in B. megaterium was also concentration dependent, and this can be related to the extent of cell membrane damage.

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Year:  1985        PMID: 3923926      PMCID: PMC238467          DOI: 10.1128/aem.49.4.904-907.1985

Source DB:  PubMed          Journal:  Appl Environ Microbiol        ISSN: 0099-2240            Impact factor:   4.792


  22 in total

1.  Inhibition by aflatonin B-1 of hydrocortisone induction of rat liver tryptophan pyrrolase and tyrosine transaminase.

Authors:  G N Wogan; M A Friedman
Journal:  Arch Biochem Biophys       Date:  1968-11       Impact factor: 4.013

2.  Microsome-dependent binding of aflatoxin B1 to DNA, RNA, polyribonucleotides and protein in vitro.

Authors:  R C Garner
Journal:  Chem Biol Interact       Date:  1973-02       Impact factor: 5.192

3.  Aflatoxin B1 binding and toxic effects on Bacillus megaterium.

Authors:  E B Lillehoj; A Ciegler
Journal:  J Gen Microbiol       Date:  1968-12

4.  Effect of aflatoxin on transcription in liver cell.

Authors:  Y Moulé; C Frayssinet
Journal:  Nature       Date:  1968-04-06       Impact factor: 49.962

Review 5.  Biological effects of aflatoxin in cell culture.

Authors:  M Legator
Journal:  Bacteriol Rev       Date:  1966-06

Review 6.  Mycotoxins: occurrence, chemistry, biological activity.

Authors:  A Ciegler
Journal:  Lloydia       Date:  1975 Jan-Feb

7.  [Aflatoxin effect on bacteria].

Authors:  J Nezval; H Bösenberg; U Linzel
Journal:  Arch Hyg Bakteriol       Date:  1970-10

8.  Antimicrobial activity of aflatoxins.

Authors:  T Arai; T Ito; Y Koyama
Journal:  J Bacteriol       Date:  1967-01       Impact factor: 3.490

9.  Production of aflatoxin on rice.

Authors:  O L Shotwell; C W Hesseltine; R D Stubblefield; W G Sorenson
Journal:  Appl Microbiol       Date:  1966-05

10.  The interaction of aflatoxins with purines and purine nucleosides.

Authors:  J I Clifford; K R Rees
Journal:  Biochem J       Date:  1967-05       Impact factor: 3.857

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  3 in total

1.  Detection and estimation of aflatoxins using both chemical and biological techniques.

Authors:  M K Refai; M E Hatem; E Sharaby; M Saad
Journal:  Mycotoxin Res       Date:  1993-03       Impact factor: 3.833

2.  Effect of nutritional factors on aflatoxin B1 inhibition of growth in Escherichia coli and Salmonella typhi.

Authors:  R P Tiwari; G Singh; N K Jain; J Singh; D V Vadehra
Journal:  Folia Microbiol (Praha)       Date:  1988       Impact factor: 2.099

Review 3.  Aflatoxin B(1) in affecting broiler's performance, immunity, and gastrointestinal tract: a review of history and contemporary issues.

Authors:  Agha W Yunus; E Razzazi-Fazeli; Josef Bohm
Journal:  Toxins (Basel)       Date:  2011-06-14       Impact factor: 4.546

  3 in total

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