Literature DB >> 3900297

Immunohistological study of granulovacuolar degeneration using monoclonal antibodies to neurofilaments.

J Kahn, B H Anderton, A Probst, J Ulrich, M M Esiri.   

Abstract

Neurons undergoing granulovacuolar degeneration have been examined in paraffin sections with three monoclonal antibodies to neurofilaments. Two of these antibodies (BF10, RT97) had been shown previously to react with neurofibrillary tangles. One of these antibodies (RT97) reacted with granular component of granulovacuolar degeneration. BF10 sometimes reacted with the surrounding neuronal cytoplasm. Granulovacuolar degeneration was also detected in a few cells of the anterior olfactory nucleus.

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Year:  1985        PMID: 3900297      PMCID: PMC1028495          DOI: 10.1136/jnnp.48.9.924

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN: 0022-3050            Impact factor:   10.154


  9 in total

1.  Clinicopathologic significance of granulovacuolar degeneration in Alzheimer's disease.

Authors:  J S WOODARD
Journal:  J Neuropathol Exp Neurol       Date:  1962-01       Impact factor: 3.685

2.  More about circumcision.

Authors:  J S Mackay
Journal:  Can Med Assoc J       Date:  1966-11-26       Impact factor: 8.262

3.  Granulovacuolar degeneration in the ageing brain and in dementia.

Authors:  M J Ball; P Lo
Journal:  J Neuropathol Exp Neurol       Date:  1977-05       Impact factor: 3.685

4.  Granulovacuolar degeneration of hippocampal pyramidal cells.

Authors:  B E Tomlinson; D Kitchener
Journal:  J Pathol       Date:  1972-03       Impact factor: 7.996

5.  The fine structure of some intraganglionic alterations. Neurofibrillary tangles, granulovacuolar bodies and "rod-like" structures as seen in Guam amyotrophic lateral sclerosis and parkinsonism-dementia complex.

Authors:  A Hirano; H M Dembitzer; L T Kurland; H M Zimmerman
Journal:  J Neuropathol Exp Neurol       Date:  1968-04       Impact factor: 3.685

6.  Monoclonal antibodies show that neurofibrillary tangles and neurofilaments share antigenic determinants.

Authors:  B H Anderton; D Breinburg; M J Downes; P J Green; B E Tomlinson; J Ulrich; J N Wood; J Kahn
Journal:  Nature       Date:  1982-07-01       Impact factor: 49.962

7.  Demonstration of neurofibrillary tangles in paraffin sections: a quick and simple method using a modification of Palmgren's method.

Authors:  R B Cross
Journal:  Med Lab Sci       Date:  1982-01

8.  The olfactory bulbs in Alzheimer's disease.

Authors:  M M Esiri; G K Wilcock
Journal:  J Neurol Neurosurg Psychiatry       Date:  1984-01       Impact factor: 10.154

9.  Topographic distribution of neurofibrillary tangles and granulovacuolar degeneration in hippocampal cortex of aging and demented patients. A quantitative study.

Authors:  M J Ball
Journal:  Acta Neuropathol       Date:  1978-05-24       Impact factor: 17.088

  9 in total
  16 in total

1.  Hydroxynonenal-generated crosslinking fluorophore accumulation in Alzheimer disease reveals a dichotomy of protein turnover.

Authors:  Xiongwei Zhu; Rudy J Castellani; Paula I Moreira; Gjumrakch Aliev; Justin C Shenk; Sandra L Siedlak; Peggy L R Harris; Hisashi Fujioka; Lawrence M Sayre; Pamela A Szweda; Luke I Szweda; Mark A Smith; George Perry
Journal:  Free Radic Biol Med       Date:  2011-11-12       Impact factor: 7.376

2.  Phosphorylated tau immunoreactivity of granulovacuolar bodies (GVB) of Alzheimer's disease: localization of two amino terminal tau epitopes in GVB.

Authors:  D W Dickson; W K Liu; Y Kress; J Ku; O DeJesus; S H Yen
Journal:  Acta Neuropathol       Date:  1993       Impact factor: 17.088

3.  Reexamination of granulovacuolar degeneration.

Authors:  K Okamoto; S Hirai; T Iizuka; T Yanagisawa; M Watanabe
Journal:  Acta Neuropathol       Date:  1991       Impact factor: 17.088

Review 4.  Changes in the ageing brain in health and disease.

Authors:  B H Anderton
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1997-12-29       Impact factor: 6.237

5.  A monoclonal antibody that recognizes a phosphorylated epitope in Alzheimer neurofibrillary tangles, neurofilaments and tau proteins immunostains granulovacuolar degeneration.

Authors:  D W Dickson; H Ksiezak-Reding; P Davies; S H Yen
Journal:  Acta Neuropathol       Date:  1987       Impact factor: 17.088

6.  Young adult-form of dementia with neurofibrillary changes and Lewy bodies.

Authors:  E R Popovitch; H M Wisniewski; M A Kaufman; I Grundke-Iqbal; G Y Wen
Journal:  Acta Neuropathol       Date:  1987       Impact factor: 17.088

7.  Staining with monoclonal antibodies to neurofilaments distinguishes between subpopulations of neurofibrillary tangles, between groups of axons and between groups of dendrites.

Authors:  J Kahn; B H Anderton; C C Miller; J N Wood; M M Esiri
Journal:  J Neurol       Date:  1987-05       Impact factor: 4.849

8.  Dementia of Alzheimer type (DAT)--a review of its morbid anatomy.

Authors:  J Ulrich; A Probst; B H Anderton; J Kahn
Journal:  Klin Wochenschr       Date:  1986-02-03

9.  New aspects of the pathology of neurodegenerative disorders as revealed by ubiquitin antibodies.

Authors:  P N Leigh; A Probst; G E Dale; D P Power; J P Brion; A Dodson; B H Anderton
Journal:  Acta Neuropathol       Date:  1989       Impact factor: 17.088

10.  Granulovacuolar degeneration in the hippocampal cortex of aging and demented patients--a quantitative study.

Authors:  M Xu; H Shibayama; H Kobayashi; K Yamada; R Ishihara; P Zhao; T Takeuchi; K Yoshida; T Inagaki; K Nokura
Journal:  Acta Neuropathol       Date:  1992       Impact factor: 17.088

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