Literature DB >> 3897194

Repair of cis-platinum-DNA adducts by ABC excinuclease in vivo and in vitro.

I Husain, S G Chaney, A Sancar.   

Abstract

cis-Platinum compounds, which are used in cancer chemotherapy, are thought to exert their effect by damaging DNA. It is known that this damage is partially repaired in Escherichia coli. Using cis-Pt-treated pBR322 DNA as a probe, we investigated the role of nucleotide excision repair in the removal of Pt-DNA adducts. We found that the nucleotide excision pathway was the major mechanism for repairing Pt adducts in transforming plasmid DNA but that a recA-dependent pathway also contributed to plasmid survival. When cis-Pt-damaged pBR322 was treated with the purified nucleotide excision enzyme ABC excinuclease in vitro, a fraction of the adducts was removed by the enzyme; this removal resulted in a corresponding increase in transformation efficiency.

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Year:  1985        PMID： 3897194      PMCID： PMC219204          DOI： 10.1128/jb.163.3.817-823.1985

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  32 in total

1.  Lack of cross-resistance between certain platinum coordination compounds in mouse leukemia.

Authors:  J H Burchenal; K Kalaher; T O'Toole; J Chisholm
Journal:  Cancer Res       Date:  1977-09       Impact factor: 12.701

2.  Determination of plasmid molecular weights from ultraviolet sensitivities.

Authors:  A Sancar; C S Rupert
Journal:  Nature       Date:  1978-03-30       Impact factor: 49.962

3.  The interaction of plantinum II compounds with bacteriophages T7 and R17.

Authors:  K V Shooter; R Howse; R K Merrifield; A B Robins
Journal:  Chem Biol Interact       Date:  1972-10       Impact factor: 5.192

4.  Platinum compounds: a new class of potent antitumour agents.

Authors:  B Rosenberg; L VanCamp; J E Trosko; V H Mansour
Journal:  Nature       Date:  1969-04-26       Impact factor: 49.962

5.  DNA-protein and DNA interstrand cross-linking by cis- and trans-platinum(II) diamminedichloride in L1210 mouse leukemia cells and relation to cytotoxicity.

Authors:  L A Zwelling; T Anderson; K W Kohn
Journal:  Cancer Res       Date:  1979-02       Impact factor: 12.701

6.  Indirect selection of bacterial plasmids lacking identifiable phenotypic properties.

Authors:  F J Kretschmer; A C Chang; S N Cohen
Journal:  J Bacteriol       Date:  1975-10       Impact factor: 3.490

7.  Effect of cis-platinum(II)diamminodichloride on wild type and deoxyribonucleic acid repair deficient mutants of Escherichia coli.

Authors:  D J Beck; R R Brubaker
Journal:  J Bacteriol       Date:  1973-12       Impact factor: 3.490

8.  Construction and characterization of new cloning vehicles. II. A multipurpose cloning system.

Authors:  F Bolivar; R L Rodriguez; P J Greene; M C Betlach; H L Heyneker; H W Boyer; J H Crosa; S Falkow
Journal:  Gene       Date:  1977       Impact factor: 3.688

9.  The chemical and biological effects of cis-dichlorodiammineplatinum (II), an antitumor agent, on DNA.

Authors:  L L Munchausen
Journal:  Proc Natl Acad Sci U S A       Date:  1974-11       Impact factor: 11.205

10.  Studies on transformations of Hemophilus influenzae. I. Competence.

Authors:  S H GOODGAL; R M HERRIOTT
Journal:  J Gen Physiol       Date:  1961-07       Impact factor: 4.086
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  15 in total

1.  Escherichia coli Fpg protein and UvrABC endonuclease repair DNA damage induced by methylene blue plus visible light in vivo and in vitro.

Authors:  H Czeczot; B Tudek; B Lambert; J Laval; S Boiteux
Journal:  J Bacteriol       Date:  1991-06       Impact factor: 3.490

2.  Transcription inhibition by platinum-DNA cross-links in live mammalian cells.

Authors:  Wee Han Ang; MyatNoeZin Myint; Stephen J Lippard
Journal:  J Am Chem Soc       Date:  2010-06-02       Impact factor: 15.419

3.  Effect of DNA polymerase I and DNA helicase II on the turnover rate of UvrABC excision nuclease.

Authors:  I Husain; B Van Houten; D C Thomas; M Abdel-Monem; A Sancar
Journal:  Proc Natl Acad Sci U S A       Date:  1985-10       Impact factor: 11.205

4.  uvrC gene function has no specific role in repair of N-2-aminofluorene adducts.

Authors:  M Bichara; R P Fuchs
Journal:  J Bacteriol       Date:  1987-01       Impact factor: 3.490

5.  Characterization of a DNA-damage-recognition protein from F9 teratocarcinoma cells, which is inducible by retinoic acid and cyclic AMP.

Authors:  C C Chao; N K Sun; S Lin-Chao
Journal:  Biochem J       Date:  1993-02-15       Impact factor: 3.857

6.  Structure of the gene complementing uvr-402 in Streptococcus pneumoniae: homology with Escherichia coli uvrB and the homologous gene in Micrococcus luteus.

Authors:  N Sicard; J Oreglia; A M Estevenon
Journal:  J Bacteriol       Date:  1992-04       Impact factor: 3.490

7.  Strategic down-regulation of DNA polymerase beta by antisense RNA sensitizes mammalian cells to specific DNA damaging agents.

Authors:  J K Horton; D K Srivastava; B Z Zmudzka; S H Wilson
Journal:  Nucleic Acids Res       Date:  1995-10-11       Impact factor: 16.971

8.  Defects in interstrand cross-link uncoupling do not account for the extreme sensitivity of ERCC1 and XPF cells to cisplatin.

Authors:  Inusha U De Silva; Peter J McHugh; Peter H Clingen; John A Hartley
Journal:  Nucleic Acids Res       Date:  2002-09-01       Impact factor: 16.971

9.  Purification of PCNA as a nucleotide excision repair protein.

Authors:  A F Nichols; A Sancar
Journal:  Nucleic Acids Res       Date:  1992-07-11       Impact factor: 16.971

10.  Ca(2+)-mediated inhibition of a nuclear protein that recognizes UV-damaged DNA and is constitutively overexpressed in resistant human cells: DNA-binding assay.

Authors:  C C Chao; S L Huang; S Lin-Chao
Journal:  Nucleic Acids Res       Date:  1991-12-11       Impact factor: 16.971
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