Literature DB >> 884687

Lack of cross-resistance between certain platinum coordination compounds in mouse leukemia.

J H Burchenal, K Kalaher, T O'Toole, J Chisholm.   

Abstract

Two congeners of cis-platinum diamminodichloride, 1,2-diamminocyclohexylplatinum malonate (NSC 224964) and 1,2-cyclohexyldiamminoplatinum sulfate (NSC 250427), show approximately equal inhibitory activity in vitro against leukemia L1210 and a line of L1210 (L1210/PDD) that has developed resistance to cis-platinum diamminodichloride. These compounds are also active against L1210/PDD in vivo. These observations suggest that they be tried clinically in patients whose disease has become resistant to cis-platinum diamminodichloride.

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Year:  1977        PMID： 884687

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  22 in total

1.  Human ovarian-carcinoma cell lines and companion xenografts: a disease-oriented approach to new platinum anticancer drug discovery.

Authors:  L R Kelland; M Jones; G Abel; M Valenti; J Gwynne; K R Harrap
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333

2.  In vitro synergism of 4-hydroperoxycyclophosphamide and cisplatin: relevance for bone marrow purging.

Authors:  R H Peters; C S Brandon; L A Avila; O M Colvin; R K Stuart
Journal:  Cancer Chemother Pharmacol       Date:  1989       Impact factor: 3.333

3.  Repair of cis-platinum-DNA adducts by ABC excinuclease in vivo and in vitro.

Authors:  I Husain; S G Chaney; A Sancar
Journal:  J Bacteriol       Date:  1985-09       Impact factor: 3.490

4.  Antitumor activity of isomeric 1,2-diaminocyclohexane platinum(IV) complexes.

Authors:  Z H Siddik; S al-Baker; G Thai; A R Khokhar
Journal:  J Cancer Res Clin Oncol       Date:  1994       Impact factor: 4.553

5.  Pharmacokinetics and tissue distribution of liposome-encapsulated cis-bis-N-decyl-iminodiacetato-1,2-diaminocyclohexane-platinum (II).

Authors:  J Lautersztain; R Perez-Soler; A R Khokhar; R A Newman; G Lopez-Berestein
Journal:  Cancer Chemother Pharmacol       Date:  1986       Impact factor: 3.333

6.  Lipophilic platinum complexes entrapped in liposomes: improved stability and preserved antitumor activity with complexes containing linear alkyl carboxylato leaving groups.

Authors:  R Perez-Soler; I Han; S al-Baker; A R Khokhar
Journal:  Cancer Chemother Pharmacol       Date:  1994       Impact factor: 3.333

7.  A phase I and pharmacology study of an oral platinum complex, JM216: dose-dependent pharmacokinetics with single-dose administration.

Authors:  M J McKeage; P Mistry; J Ward; F E Boxall; S Loh; C O'Neill; P Ellis; L R Kelland; S E Morgan; B Murrer
Journal:  Cancer Chemother Pharmacol       Date:  1995       Impact factor: 3.333

8.  Preclinical toxicity and pharmacology of liposome-entrapped cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum(II).

Authors:  R Perez-Soler; J Lautersztain; L C Stephens; K Wright; A R Khokhar
Journal:  Cancer Chemother Pharmacol       Date:  1989       Impact factor: 3.333

9.  Differential antitumor activity and toxicity of isomeric 1,2-diaminocyclohexane platinum (II) complexes.

Authors:  Z H Siddik; S al-Baker; T L Burditt; A R Khokhar
Journal:  J Cancer Res Clin Oncol       Date:  1993       Impact factor: 4.553

Review 10.  New cisplatin analogues in development. A review.

Authors:  Raymond B Weiss; Michaele C Christian
Journal:  Drugs       Date:  1993-09       Impact factor: 9.546
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