| Literature DB >> 3894562 |
Abstract
We have determined the DNA sequence of a gene encoding a thymus leukemia (TL) antigen in the BALB/c mouse, and have more definitively mapped the cloned BALB/c Tla-region class I gene clusters. Analysis of the sequence shows that the Tla gene is less closely related to the H-2 genes than H-2 genes are to one another or to a Qa-2,3-region genes. The Tla gene, 17.3A, contains an apparent gene conversion. Comparison of the BALB/c Tla genes with those from C57BL shows that BALB/c has more Tla-region class I genes, and that one of the genes absent in C57BL is gene 17.3A.Entities:
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Year: 1985 PMID: 3894562 PMCID: PMC2187753 DOI: 10.1084/jem.162.2.528
Source DB: PubMed Journal: J Exp Med ISSN: 0022-1007 Impact factor: 14.307