Literature DB >> 3879853

Measurement of blood flow, oxygen utilisation, oxygen extraction ratio, and fractional blood volume in human brain tumours and surrounding oedematous tissue.

A A Lammertsma, R J Wise, T C Cox, D G Thomas, T Jones.   

Abstract

The blood flow, oxygen utilisation, oxygen extraction ratio, and fractional blood volume were measured in brain tumours and the surrounding cerebral tissues. A total of 21 patients were studied. These included 10 primary tumours, eight secondary and three with unknown histology. Measurements were performed using the oxygen-15 steady state inhalation technique and positron emission tomography. Within the tumours no relation between blood flow, oxygen utilisation and blood volume was found. In all tumours oxygen supply was in excess of the oxygen demand of the tissues as reflected in oxygen extraction ratios that were lower than those of normal brain tissue. No indication of local ischaemia in peritumour oedema was found.

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Year:  1985        PMID： 3879853     DOI： 10.1259/0007-1285-58-692-725

Source DB:  PubMed          Journal:  Br J Radiol        ISSN： 0007-1285            Impact factor:   3.039


  23 in total

1.  Blood flow and oxygen metabolism in a case of Lhermitte-Duclos disease: results of positron emission tomography.

Authors:  K Ogasawara; T Beppu; S Yasuda; M Kobayashi; H Yukawa; A Ogawa
Journal:  J Neurooncol       Date:  2001-10       Impact factor: 4.130

2.  [Preoperative imaging as the basis for image-guided neurosurgery].

Authors:  D Winkler; G Strauss; S Hesse; A Goldammer; M Hund-Georgiadis; A Richter; O Sabri; T Kahn; J Meixensberger
Journal:  Radiologe       Date:  2004-07       Impact factor: 0.635

3.  Per- and postoperative changes in the arterio-venous oxygen content difference (AVDO2) in patients subjected to craniotomy for cerebral tumours.

Authors:  J Asmussen; S Elkjaer; G Cold; P Herlevsen; N C Melsen; M Engberg; B Hove; J Astrup
Journal:  Acta Neurochir (Wien)       Date:  1989       Impact factor: 2.216

4.  The contribution of arachidonic acid to the aetiology and pathophysiology of focal brain oedema; studies using an infusion oedema model.

Authors:  I R Whittle; I R Piper; J D Miller
Journal:  Acta Neurochir (Wien)       Date:  1991       Impact factor: 2.216

5.  Brain perfusion CT compared with ¹⁵O-H₂O PET in patients with primary brain tumours.

Authors:  Julie Marie Grüner; Rune Paamand; Michael Kosteljanetz; Helle Broholm; Liselotte Højgaard; Ian Law
Journal:  Eur J Nucl Med Mol Imaging       Date:  2012-06-27       Impact factor: 9.236

6.  MDMA ("Ecstasy") and its association with cerebrovascular accidents: preliminary findings.

Authors:  L Reneman; J B Habraken; C B Majoie; J Booij; G J den Heeten
Journal:  AJNR Am J Neuroradiol       Date:  2000 Jun-Jul       Impact factor: 3.825

Review 7.  Positron emission tomography and in vivo measurements of tumour perfusion and oxygen utilisation.

Authors:  A A Lammertsma
Journal:  Cancer Metastasis Rev       Date:  1987       Impact factor: 9.264

8.  Quantifying brain tumor blood flow by the microsphere model with N-isopropyl-p-[123I]iodoamphetamine super-early SPECT.

Authors:  H Namba; M Yanagisawa; N Yui; T Togawa; F Kinoshita; Y Iwadate; K Sueyoshi
Journal:  Ann Nucl Med       Date:  1996-02       Impact factor: 2.668

9.  Experimental transplantation gliomas in the adult cat brain. 3. Regional biochemistry.

Authors:  F Linn; K Seo; K A Hossmann
Journal:  Acta Neurochir (Wien)       Date:  1989       Impact factor: 2.216

10.  Neuropathological and neurophysiological effects of interstitial white matter autologous and non-autologous protein containing solutions: further evidence for a glioma derived permeability factor.

Authors:  I R Whittle; J W Ironside; I R Piper; J D Miller
Journal:  Acta Neurochir (Wien)       Date:  1993       Impact factor: 2.216
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