Literature DB >> 3856680

The estimation of recurrence risks in monogenic disorders using flanking marker loci.

R M Winter.   

Abstract

A method is presented of calculating recurrence risks at a disease locus where there is information from flanking marker loci. This method uses output from the computer programme LIPED. Information from carrier detection tests and mutation at the disease locus can be taken into account in certain pedigrees.

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Year:  1985        PMID： 3856680      PMCID： PMC1049370          DOI： 10.1136/jmg.22.1.12

Source DB:  PubMed          Journal:  J Med Genet        ISSN： 0022-2593            Impact factor:   6.318


  2 in total

1.  A computer program for linkage analysis of general human pedigrees.

Authors:  J Ott
Journal:  Am J Hum Genet       Date:  1976-09       Impact factor: 11.025

2.  Easy calculations of lod scores and genetic risks on small computers.

Authors:  G M Lathrop; J M Lalouel
Journal:  Am J Hum Genet       Date:  1984-03       Impact factor: 11.025
  2 in total
  2 in total

1.  A computer programme to calculate risk in X linked disorders using multiple marker loci.

Authors:  J F Clayton
Journal:  J Med Genet       Date:  1986-02       Impact factor: 6.318

2.  Estimation of the male to female ratio of mutation rates from the segregation of X-chromosomal DNA haplotypes in Duchenne muscular dystrophy families.

Authors:  C R Müller; T Grimm
Journal:  Hum Genet       Date:  1986-10       Impact factor: 4.132
  2 in total

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