| Literature DB >> 3840380 |
M R Fahey, S M Rupp, C Canfell, D M Fisher, R D Miller, M Sharma, K Castagnoli, P J Hennis.
Abstract
Patients with renal failure and undergoing a cadaver renal transplant were found to have plasma concentrations of laudanosine, following the administration of a single bolus dose of atracurium 0.5 mg kg-1, higher than those found in patients without renal failure. Since laudanosine is a known central nervous system stimulant in a variety of animal species, its actions should be investigated further in man, and particularly in patients with renal failure.Entities:
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Year: 1985 PMID： 3840380 DOI： 10.1093/bja/57.11.1049
Source DB: PubMed Journal: Br J Anaesth ISSN： 0007-0912 Impact factor: 9.166