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Literature DB >> 3819760

Olfactory threshold in Parkinson's disease.

Abstract

Olfactory threshold to differing concentrations of amyl acetate was determined in 78 subjects with idiopathic Parkinson's disease and 40 age-matched controls. Impaired olfactory threshold (previously reported by others) was confirmed in Parkinsonian subjects compared with controls. There was no significant correlation between olfactory threshold and age, sex, duration of disease, or current therapy with levodopa or anticholinergic drugs. In a sub-group of 14 levodopa-treated patients with severe "on-off" fluctuations, no change in olfactory threshold between the two states was demonstrable. Olfactory impairment in Parkinson's disease may involve mechanisms that are not influenced by pharmacologic manipulation of dopaminergic or cholinergic status.

Entities: Chemical Disease Species

Mesh：

Substances：
Pentanols
amyl acetate

Year: 1987 PMID： 3819760 PMCID： PMC1033256 DOI： 10.1136/jnnp.50.1.88

Source DB: PubMed Journal: J Neurol Neurosurg Psychiatry ISSN： 0022-3050 Impact factor: 10.154

7 in total

1. Olfactory function in patients with Parkinson's disease.

Authors: K A Ansari; A Johnson
Journal: J Chronic Dis Date: 1975-10

2. Olfactory tubercle choline acetyltransferase activity in Alzheimer-type dementia, Down's syndrome and Huntington's chorea.

Authors: J Simpson; C M Yates; A Gordon; D M St Clair
Journal: J Neurol Neurosurg Psychiatry Date: 1984-10 Impact factor: 10.154

3. The olfactory bulbs in Alzheimer's disease.

Authors: M M Esiri; G K Wilcock
Journal: J Neurol Neurosurg Psychiatry Date: 1984-01 Impact factor: 10.154

4. Olfactory impairment in Parkinson's disease.

Authors: C D Ward; W A Hess; D B Calne
Journal: Neurology Date: 1983-07 Impact factor: 9.910

5. Olfaction in dementia.

Authors: M Serby; J Corwin; A Novatt; P Conrad; J Rotrosen
Journal: J Neurol Neurosurg Psychiatry Date: 1985-08 Impact factor: 10.154

6. Demonstration and mapping of central neurons containing dopamine, noradrenaline, and 5-hydroxytryptamine and their reactions to psychopharmaca.

Authors: N A Hillarp; K Fuxe; A Dahlström
Journal: Pharmacol Rev Date: 1966-03 Impact factor: 25.468

7. N-Acetylaspartylglutamate: possible role as the neurotransmitter of the lateral olfactory tract.

Authors: J M Ffrench-Mullen; K Koller; R Zaczek; J T Coyle; N Hori; D O Carpenter
Journal: Proc Natl Acad Sci U S A Date: 1985-06 Impact factor: 11.205

7 in total

29 in total

1. An impairment in sniffing contributes to the olfactory impairment in Parkinson's disease.

Authors: N Sobel; M E Thomason; I Stappen; C M Tanner; J W Tetrud; J M Bower; E V Sullivan; J D Gabrieli
Journal: Proc Natl Acad Sci U S A Date: 2001-03-20 Impact factor: 11.205

2. A longitudinal study of olfactory function in patients with idiopathic Parkinson's disease.

Authors: Birgit Herting; Susann Schulze; Heinz Reichmann; Antje Haehner; Thomas Hummel
Journal: J Neurol Date: 2008-03-19 Impact factor: 4.849

3. Sex-related differences in olfactory function and evaluation of possible confounding factors among patients with Parkinson's disease.

Authors: P Solla; C Masala; A Liscia; R Piras; T Ercoli; L Fadda; T Hummel; A Haenher; G Defazio
Journal: J Neurol Date: 2019-09-25 Impact factor: 4.849

Olfactory threshold in Parkinson's disease.

1. Olfactory function in patients with Parkinson's disease.

2. Olfactory tubercle choline acetyltransferase activity in Alzheimer-type dementia, Down's syndrome and Huntington's chorea.

3. The olfactory bulbs in Alzheimer's disease.

4. Olfactory impairment in Parkinson's disease.

5. Olfaction in dementia.

6. Demonstration and mapping of central neurons containing dopamine, noradrenaline, and 5-hydroxytryptamine and their reactions to psychopharmaca.

7. N-Acetylaspartylglutamate: possible role as the neurotransmitter of the lateral olfactory tract.

1. An impairment in sniffing contributes to the olfactory impairment in Parkinson's disease.

2. A longitudinal study of olfactory function in patients with idiopathic Parkinson's disease.

3. Sex-related differences in olfactory function and evaluation of possible confounding factors among patients with Parkinson's disease.

4. Sall3 correlates with the expression of TH in mouse olfactory bulb.

Review 5. Olfactory Dysfunction as an Early Biomarker in Parkinson's Disease.

Review 6. Olfaction in Parkinson's disease and related disorders.

7. Amygdala pathology in Parkinson's disease.

8. Evaluation of olfactory function by topographic EEG analysis in patients with Parkinson's disease.

9. New test of odor pleasantness in Parkinson's disease.

10. Bilateral olfactory dysfunction in early stage treated and untreated idiopathic Parkinson's disease.