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Literature DB >> 6683381

Olfactory impairment in Parkinson's disease.

Abstract

In comparison with closely matched controls, patients with Parkinson's disease had reduced scores in tests of odor detection and qualitative discrimination. Olfactory impairment was not related to age, duration of symptoms, treatment, intellectual function, or genetic factors and seemed to be a nonmotor manifestation of the disease.

Entities: Disease Species

Mesh：

Year: 1983 PMID： 6683381 DOI： 10.1212/wnl.33.7.943

Source DB: PubMed Journal: Neurology ISSN： 0028-3878 Impact factor: 9.910

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Cited

32 in total

1. An impairment in sniffing contributes to the olfactory impairment in Parkinson's disease.

Authors: N Sobel; M E Thomason; I Stappen; C M Tanner; J W Tetrud; J M Bower; E V Sullivan; J D Gabrieli
Journal: Proc Natl Acad Sci U S A Date: 2001-03-20 Impact factor: 11.205

Review 2. Intranasal administration of neurotoxicants in animals: support for the olfactory vector hypothesis of Parkinson's disease.

Authors: Rui D S Prediger; Aderbal S Aguiar; Filipe C Matheus; Roger Walz; Layal Antoury; Rita Raisman-Vozari; Richard L Doty
Journal: Neurotox Res Date: 2011-10-15 Impact factor: 3.911

3. Inducible dopaminergic glutathione depletion in an α-synuclein transgenic mouse model results in age-related olfactory dysfunction.

Authors: Y H Kim; S Lussier; A Rane; S W Choi; J K Andersen
Journal: Neuroscience Date: 2010-11-03 Impact factor: 3.590

4. Olfactory threshold in Parkinson's disease.

Authors: N P Quinn; M N Rossor; C D Marsden
Journal: J Neurol Neurosurg Psychiatry Date: 1987-01 Impact factor: 10.154

5. Amygdala pathology in Parkinson's disease.

Authors: H Braak; E Braak; D Yilmazer; R A de Vos; E N Jansen; J Bohl; K Jellinger
Journal: Acta Neuropathol Date: 1994 Impact factor: 17.088

6. Increased dopaminergic neuron sensitivity to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in transgenic mice expressing mutant A53T alpha-synuclein.

Authors: Wai Haung Yu; Yasuji Matsuoka; István Sziráki; Audrey Hashim; John Lafrancois; Henry Sershen; Karen E Duff
Journal: Neurochem Res Date: 2007-11-13 Impact factor: 3.996

Olfactory impairment in Parkinson's disease.

1. An impairment in sniffing contributes to the olfactory impairment in Parkinson's disease.

Review 2. Intranasal administration of neurotoxicants in animals: support for the olfactory vector hypothesis of Parkinson's disease.

3. Inducible dopaminergic glutathione depletion in an α-synuclein transgenic mouse model results in age-related olfactory dysfunction.

4. Olfactory threshold in Parkinson's disease.

5. Amygdala pathology in Parkinson's disease.

6. Increased dopaminergic neuron sensitivity to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in transgenic mice expressing mutant A53T alpha-synuclein.

7. Vanadium exposure induces olfactory dysfunction in an animal model of metal neurotoxicity.

8. Evaluation of olfactory function by topographic EEG analysis in patients with Parkinson's disease.

9. Olfactory deficits in mice overexpressing human wildtype alpha-synuclein.

10. Regional brain stem atrophy in idiopathic Parkinson's disease detected by anatomical MRI.