| Literature DB >> 3780318 |
J Gabarrón, A Jimenez, G Glover.
Abstract
An increased frequency of mitoses showing premature centromere division (PCD) in every chromosome was found in lymphocyte cultures from four members of a subfertile family. These cells were observed in both the presence and absence of colchicine. Cultured fibroblasts from the proband showed only normal diploid metaphases. PCD cells seemed to have a shorter cell cycle. The anomaly was transmitted in a way compatible with autosomal dominant inheritance in this family.Entities:
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Year: 1986 PMID： 3780318 DOI： 10.1159/000132299
Source DB: PubMed Journal: Cytogenet Cell Genet ISSN： 0301-0171