Literature DB >> 3754961

Expression of two proopiomelanocortin genes in the pituitary gland of Xenopus laevis: complete structures of the two preprohormones.

G J Martens.   

Abstract

A number of cDNA clones corresponding to Xenopus POMC mRNA was isolated from a cDNA library constructed from Xenopus pituitary polyadenylated RNA. Characterization of the cDNA inserts revealed two groups of structurally different proopiomelanocortin mRNAs, indicating that two proopiomelanocortin genes are expressed to virtually the same level in Xenopus pituitary glands. From the mRNA structures the complete amino acid sequences of the two Xenopus preproopiomelanocortins could be deduced. Comparison with proopiomelanocortin mRNA and protein sequences from other species shows regions of high homology (including the portion of the prohormone located N-terminally of gamma-melanophore-stimulating hormone) and regions of extremely low homology (including the signal sequence).

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Year:  1986        PMID: 3754961      PMCID: PMC339815          DOI: 10.1093/nar/14.9.3791

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN: 0305-1048            Impact factor:   16.971


  34 in total

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3.  On some principles governing molecular evolution.

Authors:  M Kimura; T Ohta
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4.  DNA content in the genus Xenopus.

Authors:  C H Thiébaud; M Fischberg
Journal:  Chromosoma       Date:  1977-02-03       Impact factor: 4.316

5.  Signal sequences. The limits of variation.

Authors:  G von Heijne
Journal:  J Mol Biol       Date:  1985-07-05       Impact factor: 5.469

6.  Regulation of biosynthesis and release of pars intermedia peptides in Rana ridibunda: dopamine affects both acetylation and release of alpha-MSH.

Authors:  B G Jenks; B M Verburg van Kemenade; M C Tonon; H Vaudry
Journal:  Peptides       Date:  1985 Sep-Oct       Impact factor: 3.750

7.  Nucleotide sequence of cloned cDNA for pro-opiomelanocortin in the amphibian Xenopus laevis.

Authors:  G J Martens; O Civelli; E Herbert
Journal:  J Biol Chem       Date:  1985-11-05       Impact factor: 5.157

8.  DNA sequencing with chain-terminating inhibitors.

Authors:  F Sanger; S Nicklen; A R Coulson
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

9.  Albumin phylogeny for clawed frogs (Xenopus).

Authors:  C A Bisbee; M A Baker; A C Wilson; I Haji-Azimi; M Fischberg
Journal:  Science       Date:  1977-02-25       Impact factor: 47.728

10.  Enzymatic conversion of proteins to glycoproteins.

Authors:  D D Pless; W J Lennarz
Journal:  Proc Natl Acad Sci U S A       Date:  1977-01       Impact factor: 11.205

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  16 in total

1.  A cell-specific transgenic approach in Xenopus reveals the importance of a functional p24 system for a secretory cell.

Authors:  Gerrit Bouw; Rick Van Huizen; Eric J R Jansen; Gerard J M Martens
Journal:  Mol Biol Cell       Date:  2003-12-29       Impact factor: 4.138

2.  β-endorphin binding in cultured adrenal cortical cells.

Authors:  R A Gelfand; A Bobrow; L Pham; C Young; L Parker
Journal:  Endocrine       Date:  1995-03       Impact factor: 3.633

3.  A method for the analysis of newly synthesized tritiated mRNA.

Authors:  T A Ayoubi; D P de Kleijn; E W Roubos; G J Martens
Journal:  Nucleic Acids Res       Date:  1991-07-11       Impact factor: 16.971

4.  Nucleotide sequence of bullfrog pro-opiomelanocortin cDNA.

Authors:  F M Pan; W C Chang
Journal:  Nucleic Acids Res       Date:  1989-07-25       Impact factor: 16.971

5.  Presence of Vi-transposon-like elements in the proopiomelanocortin gene A of Xenopus laevis does not affect gene activity.

Authors:  P M Deen; E W Roubos; G J Martens
Journal:  Mol Gen Genet       Date:  1991-12

6.  Identification of domains within the V-ATPase accessory subunit Ac45 involved in V-ATPase transport and Ca2+-dependent exocytosis.

Authors:  Eric J R Jansen; Nick H M van Bakel; Nikkie F M Olde Loohuis; Theo G M Hafmans; Tim Arentsen; Anthon J M Coenen; Wim J J M Scheenen; Gerard J M Martens
Journal:  J Biol Chem       Date:  2012-06-26       Impact factor: 5.157

7.  [Leu5]enkephalin-encoding sequences are targets for a specific DNA-binding factor.

Authors:  G Bakalkin; M Telkov; T Yakovleva; L Terenius
Journal:  Proc Natl Acad Sci U S A       Date:  1995-09-26       Impact factor: 11.205

8.  D1A, D1B, and D1C dopamine receptors from Xenopus laevis.

Authors:  K S Sugamori; L L Demchyshyn; M Chung; H B Niznik
Journal:  Proc Natl Acad Sci U S A       Date:  1994-10-25       Impact factor: 11.205

9.  Comparative Functional Alanine Positional Scanning of the α-Melanocyte Stimulating Hormone and NDP-Melanocyte Stimulating Hormone Demonstrates Differential Structure-Activity Relationships at the Mouse Melanocortin Receptors.

Authors:  Aleksandar Todorovic; Mark D Ericson; Ryan D Palusak; Nicholas B Sorensen; Michael S Wood; Zhimin Xiang; Carrie Haskell-Luevano
Journal:  ACS Chem Neurosci       Date:  2016-05-17       Impact factor: 4.418

10.  Coordinated expression of 7B2 and alpha MSH in the melanotrope cells of Xenopus laevis. An immunocytochemical and in situ hybridization study.

Authors:  T A Ayoubi; H L van Duijnhoven; A J Coenen; B G Jenks; E W Roubos; G J Martens
Journal:  Cell Tissue Res       Date:  1991-05       Impact factor: 5.249

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