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Literature DB >> 4032478

Signal sequences. The limits of variation.

Abstract

Variations in length and composition of the charged N-terminal, central hydrophobic and polar C-terminal regions in a large sample of signal sequences have been mapped, both as a function of the overall length of the sequence, and in an absolute sense, i.e. various "extremes" have been sought. The results show subtle differences between eukaryotic and prokaryotic sequences, but the general impression of signal sequences as being highly variable is reinforced. Criteria for a "minimal" signal sequence are suggested and discussed.

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Year: 1985 PMID： 4032478 DOI： 10.1016/0022-2836(85)90046-4

Source DB: PubMed Journal: J Mol Biol ISSN： 0022-2836 Impact factor: 5.469

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Cited

662 in total

1. Proteophosphoglycans of Leishmania mexicana. Molecular cloning and characterization of the Leishmania mexicana ppg2 gene encoding the proteophosphoglycans aPPG and pPPG2 that are secreted by amastigotes and promastigotes.

Authors: U Göpfert; N Goehring; C Klein; T Ilg
Journal: Biochem J Date: 1999-12-15 Impact factor: 3.857

2. Cloning and characterization of a nonhemolytic phospholipase C gene from Burkholderia pseudomallei.

Authors: S Korbsrisate; N Suwanasai; A Leelaporn; T Ezaki; Y Kawamura; S Sarasombath
Journal: J Clin Microbiol Date: 1999-11 Impact factor: 5.948

3. Identification of a new gene family expressed during the onset of sexual reproduction in the centric diatom Thalassiosira weissflogii.

Authors: E V Armbrust
Journal: Appl Environ Microbiol Date: 1999-07 Impact factor: 4.792

4. CS5 pilus biosynthesis genes from enterotoxigenic Escherichia coli O115:H40.

Authors: T G Duthy; L H Staendner; P A Manning; M W Heuzenroeder
Journal: J Bacteriol Date: 1999-09 Impact factor: 3.490

5. Escherichia coli strains blocked in Tat-dependent protein export exhibit pleiotropic defects in the cell envelope.

Authors: N R Stanley; K Findlay; B C Berks; T Palmer
Journal: J Bacteriol Date: 2001-01 Impact factor: 3.490

6. Molecular and evolutionary analysis of Borrelia burgdorferi 297 circular plasmid-encoded lipoproteins with OspE- and OspF-like leader peptides.

Authors: D R Akins; M J Caimano; X Yang; F Cerna; M V Norgard; J D Radolf
Journal: Infect Immun Date: 1999-03 Impact factor: 3.441

Signal sequences. The limits of variation.

1. Proteophosphoglycans of Leishmania mexicana. Molecular cloning and characterization of the Leishmania mexicana ppg2 gene encoding the proteophosphoglycans aPPG and pPPG2 that are secreted by amastigotes and promastigotes.

2. Cloning and characterization of a nonhemolytic phospholipase C gene from Burkholderia pseudomallei.

3. Identification of a new gene family expressed during the onset of sexual reproduction in the centric diatom Thalassiosira weissflogii.

4. CS5 pilus biosynthesis genes from enterotoxigenic Escherichia coli O115:H40.

5. Escherichia coli strains blocked in Tat-dependent protein export exhibit pleiotropic defects in the cell envelope.

6. Molecular and evolutionary analysis of Borrelia burgdorferi 297 circular plasmid-encoded lipoproteins with OspE- and OspF-like leader peptides.

Review 7. Protein targeting to the bacterial cytoplasmic membrane.

8. Novel genes coding for lithotrophic sulfur oxidation of Paracoccus pantotrophus GB17.

9. Characterization of Pseudomonas aeruginosa chitinase, a gradually secreted protein.

10. Substrate-specific regulation of the ribosome- translocon junction by N-terminal signal sequences.