Literature DB >> 375009

Regulation of the biosynthesis of aminoacyl-tRNA synthetases and of tRNA in Escherichia coli. IV. Mutants with increased levels of leucyl- or seryl-tRNA synthetase.

G Theall, K B Low, D Söll.   

Abstract

Spontaneous revertants of a temperature-sensitive Escherichia coli strain harboring a thermolabile leucyl-tRNA synthetase and seryl-tRNA synthetase were selected for growth at 40 degrees C. Among these, strains were found with increased levels of both thermolabile synthetases. Two distinct genetic loci were found responsible for enzyme overproduction. leuR, located near xyl, causes elevated levels of leucyl-tRNA synthetase; while serR, located near leu, causes elevated levels of seryl-tRNA synthetase.

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Year:  1979        PMID： 375009     DOI： 10.1007/bf00271672

Source DB:  PubMed          Journal:  Mol Gen Genet        ISSN： 0026-8925


  15 in total

1.  Genetic variation in the sex factor of Escherichia coli.

Authors:  E A ADELBERG; S N BURNS
Journal:  J Bacteriol       Date:  1960-03       Impact factor: 3.490

Review 2.  Regulation of the biosynthesis of aminoacid: tRNA ligases and of tRNA.

Authors:  S D Morgan; D Söll
Journal:  Prog Nucleic Acid Res Mol Biol       Date:  1978

Review 3.  Escherichia coli K-12 F-prime factors, old and new.

Authors:  K B Low
Journal:  Bacteriol Rev       Date:  1972-12

4.  Biochemical and genetic studies with lysine+methionine mutants of Escherichia coli: lipoic acid and alpha-ketoglutarate dehydrogenase-less mutants.

Authors:  A A Herbert; J R Guest
Journal:  J Gen Microbiol       Date:  1968-10

5.  Studies on valyl-tRNA synthetase and tRNA from Escherichia coli. 3. Valyl-tRNA synthetases from thermosensitive mutants of Escherichia coli.

Authors:  M Yaniv; F Gros
Journal:  J Mol Biol       Date:  1969-08-28       Impact factor: 5.469

6.  Synthesis and inactivation of aminoacyl-transfer RNA synthetases during growth of Escherichia coli.

Authors:  L S Williams; F C Neidhardt
Journal:  J Mol Biol       Date:  1969-08-14       Impact factor: 5.469

7.  Isolation and partial characterization of temperature-sensitive Escherichia coli mutants with altered leucyl- and seryl-transfer ribonucleic acid synthetases.

Authors:  B Low; F Gates; T Goldstein; D Söll
Journal:  J Bacteriol       Date:  1971-11       Impact factor: 3.490

8.  Suppression of a defective alanyl-tRNA synthetase in Escherichia coli: a compensatory mutation to high alanine affinity.

Authors:  G Theall; K B Low; D Söll
Journal:  Mol Gen Genet       Date:  1977-11-14

9.  Close linkage of the genes serC (for phosphohydroxy pyruvate transaminase) and serS (for seryl-transfer ribonucleic acid synthetase) in Escherichia coli K-12.

Authors:  S J Clarke; B Low; W H Konigsberg
Journal:  J Bacteriol       Date:  1973-03       Impact factor: 3.490

10.  Rapid mapping of conditional and auxotrophic mutations in Escherichia coli K-12.

Authors:  B Low
Journal:  J Bacteriol       Date:  1973-02       Impact factor: 3.490
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  12 in total

Review 1.  Linkage map of Escherichia coli K-12, edition 10: the traditional map.

Authors:  M K Berlyn
Journal:  Microbiol Mol Biol Rev       Date:  1998-09       Impact factor: 11.056

2.  Molecular cloning, nucleotide sequence, and expression of shl, a new gene in the 2-minute region of the genetic map of Escherichia coli.

Authors:  G Leclerc; G Noël; G R Drapeau
Journal:  J Bacteriol       Date:  1990-08       Impact factor: 3.490

3.  Two control systems modulate the level of glutaminyl-tRNA synthetase in Escherichia coli.

Authors:  A Y Cheung; L Watson; D Söll
Journal:  J Bacteriol       Date:  1985-01       Impact factor: 3.490

4.  Regulation of the biosynthesis of aminoacyl-transfer ribonucleic acid synthetases and of transfer ribonucleic acid in Escherichia coli. V. Mutants with increased levels of valyl-transfer ribonucleic acid synthetase.

Authors:  M Baer; K B Low; D Söll
Journal:  J Bacteriol       Date:  1979-07       Impact factor: 3.490

5.  Escherichia coli K-12 lysyl-tRNA synthetase mutant with a novel reversion pattern.

Authors:  I N Hirshfield; R Tenreiro; R A Vanbogelen; F C Neidhardt
Journal:  J Bacteriol       Date:  1984-05       Impact factor: 3.490

6.  Regulation of tryptophanyl-tRNA synthetase formation.

Authors:  C V Hall; C Yanofsky
Journal:  J Bacteriol       Date:  1982-08       Impact factor: 3.490

7.  Genetic analysis of mutations causing borrelidin resistance by overproduction of threonyl-transfer ribonucleic acid synthetase.

Authors:  J Fröhler; A Rechenmacher; J Thomale; G Nass; A Böck
Journal:  J Bacteriol       Date:  1980-09       Impact factor: 3.490

Review 8.  Linkage map of Escherichia coli K-12, edition 6.

Authors:  B J Bachmann; K B Low
Journal:  Microbiol Rev       Date:  1980-03

9.  Regulation of the biosynthesis of aminoacyl-transfer ribonucleic acid synthetases and of transfer ribonucleic acid in Escherichia coli. VI. Mutants with increased levels of glutaminyl-transfer ribonucleic acid synthetase and of glutamine transfer ribonucleic acid.

Authors:  A Cheung; S Morgan; K B Low; D Söll
Journal:  J Bacteriol       Date:  1979-07       Impact factor: 3.490

Review 10.  Functions of the gene products of Escherichia coli.

Authors:  M Riley
Journal:  Microbiol Rev       Date:  1993-12
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