Literature DB >> 3742153

The hypothermic action of carbachol in the rat brain periaqueductal grey area may involve neurotensin.

E C Griffiths, P Slater, P S Widdowson.   

Abstract

Neurotensin (NT) and carbachol both caused hypothermia when injected into the periaqueductal grey area (PAG) of rat brain. Atropine prevented carbachol- but not NT-induced hypothermia. NT-induced hypothermia was unaffected by various neurotransmitter agonists and antagonists in the PAG. Both NT antibodies and thyrotrophin releasing hormone prevented carbachol hypothermia. It is concluded that the hypothermic action of carbachol in the PAG is mediated via endogenous NT.

Entities:  

Mesh：

Substances：

Year:  1986        PMID： 3742153      PMCID： PMC1916974          DOI： 10.1111/j.1476-5381.1986.tb10247.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  19 in total

1.  Hypothermia and intolerance to cold induced by intracisternal administration of the hypothalamic peptide neurotensin.

Authors:  G Bissette; C B Nemeroff; P T Loosen; A J Prange; M A Lipton
Journal:  Nature       Date:  1976-08-12       Impact factor: 49.962

2.  Neurotensin receptor binding, regional and subcellular distributions favor transmitter role.

Authors:  G R Uhl; S H Snyder
Journal:  Eur J Pharmacol       Date:  1977-01-07       Impact factor: 4.432

3.  Neurotensin: immunohistochemical localization in rat central nervous system.

Authors:  G R Uhl; M J Kuhar; S H Snyder
Journal:  Proc Natl Acad Sci U S A       Date:  1977-09       Impact factor: 11.205

4.  Cortical projections to the periaqueductal grey in the cat: a retrograde horseradish peroxidase study.

Authors:  E O Bragin; Z V Yeliseeva; G F Vasilenko; E E Meizerov; B T Chuvin; R A Durinyan
Journal:  Neurosci Lett       Date:  1984-10-12       Impact factor: 3.046

5.  Neurotensin-containing cell bodies, fibers and nerve terminals in the brain stem of the rat: immunohistochemical mapping.

Authors:  G R Uhl; R R Goodman; S H Snyder
Journal:  Brain Res       Date:  1979-05-05       Impact factor: 3.252

6.  Neurotensin: central nervous system effects of a hypothalamic peptide.

Authors:  C B Nemeroff; G Bissette; A J Prange; P T Loosen; T S Barlow; M A Lipton
Journal:  Brain Res       Date:  1977-06-17       Impact factor: 3.252

7.  Differential neurobehavioral effects of neurotensin and structural analogues.

Authors:  F B Jolicoeur; A Barbeau; F Rioux; R Quirion; S St-Pierre
Journal:  Peptides       Date:  1981       Impact factor: 3.750

8.  Hypothermia elicited by the intracerebral microinjection of neurotensin.

Authors:  G E Martin; C B Bacino; N L Papp
Journal:  Peptides       Date:  1980       Impact factor: 3.750

9.  Immunocytochemical localization of beta-endorphin-containing neurons in the rat brain.

Authors:  J C Finley; P Lindström; P Petrusz
Journal:  Neuroendocrinology       Date:  1981-07       Impact factor: 4.914

10.  Muscarinic receptors in the central nervous system of the rat. II. Distribution of binding of [3H]propylbenzilylcholine mustard in the midbrain and hindbrain.

Authors:  A Rotter; N J Birdsall; P M Field; G Raisman
Journal:  Brain Res       Date:  1979       Impact factor: 3.252
View more
  2 in total

1.  Thermogenic effects of thyrotrophin-releasing hormone and its analogues in the rat.

Authors:  E C Griffiths; N J Rothwell; M J Stock
Journal:  Experientia       Date:  1988-01-15

Review 2.  To ingest or rest? Specialized roles of lateral hypothalamic area neurons in coordinating energy balance.

Authors:  Juliette A Brown; Hillary L Woodworth; Gina M Leinninger
Journal:  Front Syst Neurosci       Date:  2015-02-18
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.