Literature DB >> 3731675

Pharmacodynamic and pharmacokinetic differences between drug enantiomers in humans: an overview.

D E Drayer.   

Abstract

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Year:  1986        PMID: 3731675     DOI: 10.1038/clpt.1986.150

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN: 0009-9236            Impact factor:   6.875


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  45 in total

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2.  Influence of stereoselective pharmacokinetics in the development and predictability of an IVIVC for the enantiomers of metoprolol tartrate.

Authors:  N Sirisuth; N D Eddington
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Review 3.  Stereoselectivity in clinical pharmacokinetics and drug development.

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4.  Racemic therapeutics--ethical and regulatory aspects.

Authors:  E J Ariëns
Journal:  Eur J Clin Pharmacol       Date:  1991       Impact factor: 2.953

Review 5.  Clinical pharmacology through the looking glass: reflections on the racemate vs enantiomer debate.

Authors:  M S Lennard
Journal:  Br J Clin Pharmacol       Date:  1991-06       Impact factor: 4.335

Review 6.  Stereoselectivity in pharmacokinetics: a general theory.

Authors:  R H Levy; A V Boddy
Journal:  Pharm Res       Date:  1991-05       Impact factor: 4.200

7.  Stereoselective dissolution of propranolol hydrochloride from hydroxypropyl methylcellulose matrices.

Authors:  S P Duddu; M Vakilynejad; F Jamali; D J Grant
Journal:  Pharm Res       Date:  1993-11       Impact factor: 4.200

8.  Mode of Action Studies on a Chiral Diphenyl Ether Peroxidizing Herbicide: Correlation between Differential Inhibition of Protoporphyrinogen IX Oxidase Activity and Induction of Tetrapyrrole Accumulation by the Enantiomers.

Authors:  B J Hallahan; P Camilleri; A Smith; J R Bowyer
Journal:  Plant Physiol       Date:  1992-11       Impact factor: 8.340

9.  Use of pseudoracemic nitrendipine to elucidate the metabolic steps responsible for stereoselective disposition of nitrendipine enantiomers.

Authors:  V Mast; C Fischer; G Mikus; M Eichelbaum
Journal:  Br J Clin Pharmacol       Date:  1992-01       Impact factor: 4.335

10.  Stereospecific high-performance liquid chromatographic assay of sotalol in plasma.

Authors:  R A Carr; R T Foster; N H Bhanji
Journal:  Pharm Res       Date:  1991-09       Impact factor: 4.200

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