Literature DB >> 372248

A new antigen on the epithelial membrane: its immunoperoxidase localisation in normal and neoplastic tissue.

E Heyderman, K Steele, M G Ormerod.   

Abstract

Using antisera raised against defatted human cream we have demonstrated a new antigen on the epithelial membrane. An indirect immunoperoxidase technique on routinely processed histological sections was used, and we describe results which show that this antigen has a widespread but highly selective distribution, being apparently localised to membranes that have a secretory function. The antigen is carried by a variety of adenocarcinomas, suggesting that its localisation may have a role in the diagnosis and differential diagnosis of malignant disease.

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Year:  1979        PMID： 372248      PMCID： PMC1145564          DOI： 10.1136/jcp.32.1.35

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN： 0021-9746            Impact factor:   3.411


  10 in total

1.  Identification of a new oncofoetal antigen associated with several types of human carcinomas.

Authors:  R Fritsché; J Mach
Journal:  Nature       Date:  1975-12-25       Impact factor: 49.962

2.  Surface differentiation antigens of human mammary epithelial cells carried on the human milk fat globule.

Authors:  R L Ceriani; K Thompson; J A Peterson; S Abraham
Journal:  Proc Natl Acad Sci U S A       Date:  1977-02       Impact factor: 11.205

3.  A shorter immunoperoxidase technique for the demonstration of carcinoembryonic antigen and other cell products.

Authors:  E Heyderman; A M Neville
Journal:  J Clin Pathol       Date:  1977-02       Impact factor: 3.411

4.  A human cell line from a pleural effusion derived from a breast carcinoma.

Authors:  H D Soule; J Vazguez; A Long; S Albert; M Brennan
Journal:  J Natl Cancer Inst       Date:  1973-11       Impact factor: 13.506

5.  Peroxidase-labeled antibody. A new method of conjugation.

Authors:  P K Nakane; A Kawaoi
Journal:  J Histochem Cytochem       Date:  1974-12       Impact factor: 2.479

6.  Identification of an antigen from normal human tissue that crossreacts with the carcinoembryonic antigen.

Authors:  S von Kleist; G Chavanel; P Burtin
Journal:  Proc Natl Acad Sci U S A       Date:  1972-09       Impact factor: 11.205

7.  Characterization and isolation of specific renal tubular epithelial antigens.

Authors:  T S Edgington; R J Glassock; J I Watson; F J Dixon
Journal:  J Immunol       Date:  1967-12       Impact factor: 5.422

8.  Immunofluorescent localization of Tamm-Horsfall mucoprotein.

Authors:  T Friedman
Journal:  Experientia       Date:  1966-09-15

9.  Carcinoembryonic antigen: immunohistologic identification in invasive and intraepithelial carcinomas of the lung.

Authors:  R R Pascal; R Mesa-Tejada; S J Bennett; A Garces; C M Fenoglio
Journal:  Arch Pathol Lab Med       Date:  1977-11       Impact factor: 5.534

10.  Evaluation of a breast cyst fluid protein detectable in the plasma of breast carcinoma patients.

Authors:  D E Haagensen; G Mazoujian; W D Holder; S J Kister; S A Wells
Journal:  Ann Surg       Date:  1977-03       Impact factor: 12.969
  10 in total
  83 in total

1.  Evidence of vascular differentiation in anaplastic tumours of the thyroid--an immunohistological study.

Authors:  F Eckert; U Schmid; F Gloor; C Hedinger
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1986

2.  Antibodies to normal human colon membranes: preparation, characterization and tissue distribution.

Authors:  R J Nicholls; J Southgate; L K Trejdosiewicz
Journal:  Histochem J       Date:  1985-06

3.  Merkel cell (small cell) carcinoma of the skin: immunohistochemical and ultrastructural demonstration of distinctive perinuclear cytokeratin aggregates and a possible association with B cell neoplasms.

Authors:  F P Kuhajda; J L Olson; R B Mann
Journal:  Histochem J       Date:  1986-05

Review 4.  Immunoperoxidase technique in histopathology: applications, methods, and controls.

Authors:  E Heyderman
Journal:  J Clin Pathol       Date:  1979-10       Impact factor: 3.411

5.  Advances in pathology and immunocytochemistry.

Authors:  E Heyderman
Journal:  J R Soc Med       Date:  1985       Impact factor: 5.344

6.  Expression in normal adult, fetal, and neoplastic tissues of a carbohydrate differentiation antigen recognised by antigranulocyte mouse monoclonal antibodies.

Authors:  N C McCarthy; J R Simpson; G Coghill; M A Kerr
Journal:  J Clin Pathol       Date:  1985-05       Impact factor: 3.411

7.  Non-Hodgkin's lymphoma involving the brain. Diagnostic usefulness of stereotactic needle biopsy in combination with paraffin-section immunohistochemistry.

Authors:  H Nakamine; H Yokote; T Itakura; S Hayashi; N Komai; Y Takano; K Saito; H Moriwaki; E Nishino; T Takenaka
Journal:  Acta Neuropathol       Date:  1989       Impact factor: 17.088

8.  Immunohistochemical reactivity of a monoclonal antibody prepared against human breast carcinoma.

Authors:  R Mariani-Costantini; M I Colnaghi; F Leoni; S Mènard; S Cerasoli; F Rilke
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1984

9.  The presence and significance of the Thomsen-Friedenreich antigen in breast cancer. I. Serological studies.

Authors:  R A Newman; P J Klein; G Uhlenbruck; P Citoler; D Karduck
Journal:  J Cancer Res Clin Oncol       Date:  1979-02-19       Impact factor: 4.553

10.  Isolation and chemical and immunochemical characterization of the peanut-lectin-binding glycoprotein from human milk-fat-globule membranes.

Authors:  J Fischer; P J Klein; G H Farrar; F G Hanisch; G Uhlenbruck
Journal:  Biochem J       Date:  1984-12-01       Impact factor: 3.857
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