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Literature DB >> 3099463

Evidence of vascular differentiation in anaplastic tumours of the thyroid--an immunohistological study.

F Eckert, U Schmid, F Gloor, C Hedinger.

Abstract

Sixteen cases of anaplastic carcinoma (ACA) and 4 cases of malignant haemangioendothelioma (HAE) of the thyroid were studied by light microscopy and immunohistochemistry. Seven cases of ACA and 3 cases of HAE were characterized by coexpression of immunohistological features of epithelial and vascular endothelial cells. Expression of vimentin was common to all tumours investigated. The present study provides evidence that ACA and HAE are partially closely related tumours showing alternating differentiation. This speaks in favour of a common neoplastic cell with the potential for epithelial and vascular endothelial differentiation.

Entities: Disease Gene

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Year: 1986 PMID： 3099463 DOI： 10.1007/bf00710826

Source DB: PubMed Journal: Virchows Arch A Pathol Anat Histopathol ISSN： 0174-7398

52 in total

Evidence of vascular differentiation in anaplastic tumours of the thyroid--an immunohistological study.

1. Histogenesis and differentiation: a re-evaluation of these concepts as criteria for the classification of tumors.

2. Different intermediate-sized filaments distinguished by immunofluorescence microscopy.

3. The use of proteolytic enzymes to improve immunoglobulin staining by the PAP technique.

4. Pathology of thyroid tumors: some recent and old questions.

5. Factor VIII related antigen and mast cells.

6. Lectins as fluorescence microscopic markers for saccharides in the human kidney.

7. Synthesis of antihemophilic factor antigen by cultured human endothelial cells.

8. Factor VII related antigen as an endothelial cell marker in benign and malignant diseases.

9. Thyroglobulin in carcinoma of the thyroid: an immunohistochemical study.

10. Intermediate-sized filaments of human endothelial cells.

1. The biological characteristics and chemosensitivity of anaplastic thyroid carcinoma transplanted into nude mice.

Review 2. Angiosarcoma of the thyroid: a case report with review of the literature.

3. Epithelioid angiosarcoma of the thyroid. Clinicopathological analysis of seven cases from non-Alpine areas.

Review 4. Diagnostic controversies in vascular proliferations of the thyroid gland.

5. Peripheral Nerve Sheath Tumors of the Thyroid Gland: A Series of Four Cases and a Review of the Literature.

6. Nonalpine thyroid angiosarcoma in a patient with hashimoto thyroiditis.

7. Primary Epithelioid Angiosarcoma of the Thyroid in a Patient Occupationally Exposed to Radiations.

Review 8. Thyroid leiomyosarcoma: presentation of two cases and review of the literature.