Literature DB >> 3717253

Drop size of commercial glaucoma medications.

C M Lederer, R E Harold.   

Abstract

We tested 145 samples of 20 different topical medications for the treatment of glaucoma to determine the average drop size of each preparation. The average drop volumes of different preparations varied between a minimum of 25.1 microliter and a maximum of 56.4 microliter, with an average drop volume of 39.0 microliter. Our findings contradict the common assumption that commercial eyedrops contain a volume of 50 to 75 microliters.

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Year:  1986        PMID： 3717253     DOI： 10.1016/0002-9394(86)90771-3

Source DB:  PubMed          Journal:  Am J Ophthalmol        ISSN： 0002-9394            Impact factor:   5.258


  10 in total

1.  Dosing problems in the use of topical ophthalmic drops.

Authors:  A Loewenstein; O Geyer; A Blanc; M Lazar
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1992       Impact factor: 3.117

2.  A study of the causes of non-compliance by patients prescribed eyedrops.

Authors:  A J Winfield; D Jessiman; A Williams; L Esakowitz
Journal:  Br J Ophthalmol       Date:  1990-08       Impact factor: 4.638

3.  Influence of the strength, drop size and viscosity of metipranolol eye drops on the concentration of the substance in human aqueous humour.

Authors:  C Kessler; H Bleckmann; G Kleintges
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  1991       Impact factor: 3.117

4.  Diffusion of Antimicrobials Across Silicone Hydrogel Contact Lenses.

Authors:  Alison M Zambelli; Kimberly M Brothers; Kristin M Hunt; Eric G Romanowski; Amy C Nau; Deepinder K Dhaliwal; Robert M Q Shanks
Journal:  Eye Contact Lens       Date:  2015-09       Impact factor: 2.018

5.  Lyophilisates for drug delivery in ophthalmology: pharmacokinetics of fluorescein in the human anterior segment.

Authors:  S Dinslage; M Diestelhorst; A Weichselbaum; R Süverkrüp
Journal:  Br J Ophthalmol       Date:  2002-10       Impact factor: 4.638

6.  Rational use of the fixed combination of dorzolamide - timolol in the management of raised intraocular pressure and glaucoma.

Authors:  Jason Yeh; Daniel Kravitz; Brian Francis
Journal:  Clin Ophthalmol       Date:  2008-06

7.  Reduction in drop size of ophthalmic topical drop preparations and the impact of treatment.

Authors:  Shiva Kumar; Roopa Karki; Marreddy Meena; Tigari Prakash; Tanniru Rajeswari; Divakar Goli
Journal:  J Adv Pharm Technol Res       Date:  2011-07

8.  Proficiency of eye drop instillation in postoperative cataract patients in Ghana.

Authors:  Yang Liu; Amanda Murdoch; Ken Bassett; Shafik Dharamsi
Journal:  Clin Ophthalmol       Date:  2013-10-29

9.  A comparative study on efficacy of fixed combination timolol/brinzolamide versus travoprost monotherapy in drug-naïve open-angle glaucoma patients.

Authors:  Alok Dixit; Atul Ashish; Reena Sharma
Journal:  Ther Adv Ophthalmol       Date:  2020-04-28

Review 10.  Formulation Considerations for the Management of Dry Eye Disease.

Authors:  Priyanka Agarwal; Jennifer P Craig; Ilva D Rupenthal
Journal:  Pharmaceutics       Date:  2021-02-03       Impact factor: 6.321
  10 in total

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