Literature DB >> 3712377

Considerations for the design of nitrophenyl mustards as agents with selective toxicity for hypoxic tumor cells.

W A Denny, W R Wilson.   

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Year:  1986        PMID： 3712377     DOI： 10.1021/jm00156a001

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  14 in total

Review 1.  Recent developments in the design of bioreductive drugs.

Authors:  W A Denny; W R Wilson; M P Hay
Journal:  Br J Cancer Suppl       Date:  1996-07

2.  Amine prodrugs which utilize hydroxy amide lactonization. I. A potential redox-sensitive amide prodrug.

Authors:  K L Amsberry; R T Borchardt
Journal:  Pharm Res       Date:  1991-03       Impact factor: 4.200

Review 3.  Interfering with pH regulation in tumours as a therapeutic strategy.

Authors:  Dario Neri; Claudiu T Supuran
Journal:  Nat Rev Drug Discov       Date:  2011-09-16       Impact factor: 84.694

4.  Tertiary amine N-oxides as bioreductive drugs: DACA N-oxide, nitracrine N-oxide and AQ4N.

Authors:  W R Wilson; W A Denny; S M Pullen; K M Thompson; A E Li; L H Patterson; H H Lee
Journal:  Br J Cancer Suppl       Date:  1996-07

5.  Hypoxia-selective, enzymatic conversion of 6-nitroquinoline into a fluorescent helicene: pyrido[3,2-f]quinolino[6,5-c]cinnoline 3-oxide.

Authors:  Anuruddha Rajapakse; Kent S Gates
Journal:  J Org Chem       Date:  2012-03-19       Impact factor: 4.354

6.  5-Dimethyl-amino-N,N-dimethyl-2-nitro-benzamide.

Authors:  Hoong-Kun Fun; Samuel Robinson Jebas; B Chandrakantha; Vijaya Padmar; Arun M Isloor
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-05-20

7.  Enzymatic conversion of 6-nitroquinoline to the fluorophore 6-aminoquinoline selectively under hypoxic conditions.

Authors:  Anuruddha Rajapakse; Collette Linder; Ryan D Morrison; Ujjal Sarkar; Nathan D Leigh; Charles L Barnes; J Scott Daniels; Kent S Gates
Journal:  Chem Res Toxicol       Date:  2013-04-02       Impact factor: 3.739

8.  Necrosis in non-tumour tissues caused by flavone acetic acid and 5,6-dimethyl xanthenone acetic acid.

Authors:  L J Zwi; B C Baguley; J B Gavin; W R Wilson
Journal:  Br J Cancer       Date:  1990-12       Impact factor: 7.640

Review 9.  Therapeutic targeting of the hypoxic tumour microenvironment.

Authors:  Dean C Singleton; Andrew Macann; William R Wilson
Journal:  Nat Rev Clin Oncol       Date:  2021-07-29       Impact factor: 66.675

Review 10.  The experimental development of bioreductive drugs and their role in cancer therapy.

Authors:  P Workman; I J Stratford
Journal:  Cancer Metastasis Rev       Date:  1993-06       Impact factor: 9.264
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