Literature DB >> 3697086

Preparation of the individual diastereomers of adenylyl-(2'-5')-P-thioadenylyl-(2'-5')-adenosine and their 5'-phosphorylated derivatives.

E de Vroom1, A Fidder, C P Saris, G A van der Marel, J H van Boom.   

Abstract

The individual diastereomers of trimer A2'p5'A2'p(s)5'A, containing one phosphorothioate linkage, were prepared via a modified hydroxybenzotriazole phosphotriester approach. The 5'-phosphorylated derivatives of the latter compounds were obtained after phosphorylation with a 6-trifluoromethyl-1-benzotriazolyl activated phosphoromorpholidate.

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Year:  1987        PMID： 3697086      PMCID： PMC306541          DOI： 10.1093/nar/15.23.9933

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  27 in total

1.  An interferon-induced phosphodiesterase degrading (2'-5') oligoisoadenylate and the C-C-A terminus of tRNA.

Authors:  A Schmidt; Y Chernajovsky; L Shulman; P Federman; H Berissi; M Revel
Journal:  Proc Natl Acad Sci U S A       Date:  1979-10       Impact factor: 11.205

2.  Interferon action may be mediated by activation of a nuclease by pppA2'p5'A2'p5'A.

Authors:  C Baglioni; M A Minks; P A Maroney
Journal:  Nature       Date:  1978-06-22       Impact factor: 49.962

3.  pppA2'p5'A2'p5'A: an inhibitor of protein synthesis synthesized with an enzyme fraction from interferon-treated cells.

Authors:  I M Kerr; R E Brown
Journal:  Proc Natl Acad Sci U S A       Date:  1978-01       Impact factor: 11.205

4.  Rapid chemical synthesis and circular dichroism properties of some 2'-5'-linked oligoriboadenylates.

Authors:  A F Markham; R A Porter; M J Gait; R C Sheppard; I M Kerr
Journal:  Nucleic Acids Res       Date:  1979-06-11       Impact factor: 16.971

5.  The synthesis of oligoribonucleotides. IV. Preparation of dinucleoside phosphates from 2',5'-protected ribonucleoside derivatives.

Authors:  B E Griffin; M Jarman; C B Reese
Journal:  Tetrahedron       Date:  1968-01       Impact factor: 2.457

6.  The cordycepin analogue of 2,5A and its threo isomer. Chemical synthesis, conformation and biological activity.

Authors:  A Nyilas; L Vrang; A Drake; B Oberg; J Chattopadhyaya
Journal:  Acta Chem Scand B       Date:  1986-09

7.  Synthesis and characterization of (2'-5')ppp3'dA(p3'dA)n, an analogue of (2'-5')pppA(pA)n.

Authors:  P Doetsch; J M Wu; Y Sawada; R J Suhadolnik
Journal:  Nature       Date:  1981-05-28       Impact factor: 49.962

8.  Inhibition of cell-free protein synthesis by pppA2'p5'A2'p5'A: a novel oligonucleotide synthesized by interferon-treated L cell extracts.

Authors:  M J Clemens; B R Williams
Journal:  Cell       Date:  1978-03       Impact factor: 41.582

9.  Analogs of (2'-5')oligo(A). Endonuclease activation and inhibition of protein synthesis in intact cells.

Authors:  C Baglioni; S B D'Alessandro; T W Nilsen; J A den Hartog; R Crea; J H van Boom
Journal:  J Biol Chem       Date:  1981-04-10       Impact factor: 5.157

10.  Arylsulfonyltetrazoles, new coupling reagents and further improvements in the triester method for the synthesis of deoxyribooligonucleotides.

Authors:  J Stawinski; T Hozumi; S A Narang; C P Bahl; R Wu
Journal:  Nucleic Acids Res       Date:  1977-02       Impact factor: 16.971
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  1 in total

Review 1.  The 2-5A system: modulation of viral and cellular processes through acceleration of RNA degradation.

Authors:  M R Player; P F Torrence
Journal:  Pharmacol Ther       Date:  1998-05       Impact factor: 12.310
  1 in total

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