Literature DB >> 3687587

The effects of 5-lipoxygenase inhibitors and leukotriene antagonists on the development of gastric lesions induced by nonsteroidal antiinflammatory drugs in mice.

K D Rainsford1.   

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Year:  1987        PMID: 3687587     DOI: 10.1007/bf01966502

Source DB:  PubMed          Journal:  Agents Actions        ISSN: 0065-4299


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  11 in total

1.  Synthesis of [[(naphthalenylmethoxy)- and [[(quinolinylmethoxy)phenyl]amino]oxoalkanoic acid esters. A novel series of leukotriene D4 antagonists and 5-lipoxygenase inhibitors.

Authors:  J H Musser; D M Kubrak; J Chang; A J Lewis
Journal:  J Med Chem       Date:  1986-08       Impact factor: 7.446

Review 2.  Autonomic pharmacology of leukotrienes.

Authors:  G Feuerstein
Journal:  J Auton Pharmacol       Date:  1985-06

3.  Evidence for differing leukotriene receptors in gastric mucosa.

Authors:  R G Pendleton; J R Stavorski
Journal:  Eur J Pharmacol       Date:  1986-06-17       Impact factor: 4.432

4.  Selective inhibition of leukotriene C4 synthesis in human neutrophils by ethacrynic acid.

Authors:  K H Leung
Journal:  Biochem Biophys Res Commun       Date:  1986-05-29       Impact factor: 3.575

5.  Gastric ulcerogenicity of non-steroidal anti-inflammatory drugs in mice with mucosa sensitized by cholinomimetic treatment.

Authors:  K D Rainsford
Journal:  J Pharm Pharmacol       Date:  1987-08       Impact factor: 3.765

6.  L-649,923, sodium (beta S*, gamma R*)-4-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)-propylthio)- gamma-hydroxy-beta-methylbenzenebutanoate, a selective, orally active leukotriene receptor antagonist.

Authors:  T R Jones; R Young; E Champion; L Charette; D Denis; A W Ford-Hutchinson; R Frenette; J Y Gauthier; Y Guindon; M Kakushima
Journal:  Can J Physiol Pharmacol       Date:  1986-08       Impact factor: 2.273

7.  Comparison of the action of cholinomimetics and pentagastrin on gastric secretion in dogs.

Authors:  D F Magee; S Naruse; A Pap
Journal:  Br J Pharmacol       Date:  1985-02       Impact factor: 8.739

8.  Arachidonic acid metabolites and the gastro-intestinal toxicity of anti-inflammatory agents.

Authors:  B J Whittle
Journal:  Prostaglandins       Date:  1981

9.  Investigation of the vascular actions of arachidonate lipoxygenase and cyclo-oxygenase products on the isolated perfused stomach of rat and rabbit.

Authors:  P Salvati; B J Whittle
Journal:  Prostaglandins       Date:  1981-07

10.  LY171883, 1-less than 2-hydroxy-3-propyl-4-less than 4-(1H-tetrazol-5-yl) butoxy greater than phenyl greater than ethanone, an orally active leukotriene D4 antagonist.

Authors:  J H Fleisch; L E Rinkema; K D Haisch; D Swanson-Bean; T Goodson; P P Ho; W S Marshall
Journal:  J Pharmacol Exp Ther       Date:  1985-04       Impact factor: 4.030

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  26 in total

Review 1.  Non-steroidal anti-inflammatory drug-induced gastropathy. Mechanisms and management.

Authors:  S Szabo; W F Spill; K D Rainsford
Journal:  Med Toxicol Adverse Drug Exp       Date:  1989 Mar-Apr

2.  Flavocoxid, a dual inhibitor of cyclooxygenase-2 and 5-lipoxygenase, reduces pancreatic damage in an experimental model of acute pancreatitis.

Authors:  F Polito; A Bitto; N Irrera; F Squadrito; C Fazzari; L Minutoli; D Altavilla
Journal:  Br J Pharmacol       Date:  2010-11       Impact factor: 8.739

3.  Antiulcerogenic activity of ethanolic leaf extract of Lasianthera africana.

Authors:  Jude E Okokon; Bassey S Antia; Emem E Umoh
Journal:  Afr J Tradit Complement Altern Med       Date:  2009-03-07

Review 4.  The role of prostaglandins in gastric mucosal protection.

Authors:  D E Wilson
Journal:  Trans Am Clin Climatol Assoc       Date:  1996

Review 5.  Cyclo-oxygenase isoenzymes. How recent findings affect thinking about nonsteroidal anti-inflammatory drugs.

Authors:  J Y Jouzeau; B Terlain; A Abid; E Nédélec; P Netter
Journal:  Drugs       Date:  1997-04       Impact factor: 9.546

6.  Proceedings of the British Pharmacological Society. London, 19th-21st December. Abstracts.

Authors: 
Journal:  Br J Pharmacol       Date:  1989-03       Impact factor: 8.739

7.  Determination of the antiulcer properties of sodium cromoglycate in pylorus-ligated albino rats.

Authors:  Vivek Srivastava; A H M Viswanathaswamy; Govind Mohan
Journal:  Indian J Pharmacol       Date:  2010-06       Impact factor: 1.200

8.  Eicosanoid and gastroprotection by copper derivatives and NDGA.

Authors:  L Franco; G P Velo
Journal:  Inflamm Res       Date:  1995-03       Impact factor: 4.575

9.  Leukotrienes in the pathogenesis of NSAID-induced gastric and intestinal mucosal damage.

Authors:  K D Rainsford
Journal:  Agents Actions       Date:  1993

Review 10.  The problems and pitfalls of NSAID therapy in the elderly (Part II).

Authors:  A G Johnson; R O Day
Journal:  Drugs Aging       Date:  1991-05       Impact factor: 3.923

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