Literature DB >> 36252052

MonOrail to Cure? Targeting Orai1 to Reverse Pulmonary Arterial Hypertension.

Tatiana V Kudryashova1, Elena A Goncharova1.   

Abstract

Entities:  

Keywords:  Editorials; ORAI1 Protein; hypertension, pulmonary; muscle, smooth, vascular; pulmonary artery; translational science, biomedical; vascular remodeling

Mesh：

Substances：

Year:  2022        PMID： 36252052      PMCID： PMC9586488          DOI： 10.1161/CIRCRESAHA.122.321924

Source DB:  PubMed          Journal:  Circ Res        ISSN： 0009-7330            Impact factor:   23.213


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  15 in total

1.  Orai1, STIM1, and iPLA2β determine arterial vasoconstriction.

Authors:  Victoria M Bolotina
Journal:  Arterioscler Thromb Vasc Biol       Date:  2012-05       Impact factor: 8.311

Review 2.  Calcium Channels in Vascular Smooth Muscle.

Authors:  D Ghosh; A U Syed; M P Prada; M A Nystoriak; L F Santana; M Nieves-Cintrón; M F Navedo
Journal:  Adv Pharmacol       Date:  2016-10-14

Review 3.  Translational Advances in the Field of Pulmonary Hypertension. From Cancer Biology to New Pulmonary Arterial Hypertension Therapeutics. Targeting Cell Growth and Proliferation Signaling Hubs.

Authors:  Soni Savai Pullamsetti; Rajkumar Savai; Werner Seeger; Elena A Goncharova
Journal:  Am J Respir Crit Care Med       Date:  2017-02-15       Impact factor: 21.405

4.  PDGF enhances store-operated Ca2+ entry by upregulating STIM1/Orai1 via activation of Akt/mTOR in human pulmonary arterial smooth muscle cells.

Authors:  Aiko Ogawa; Amy L Firth; Kimberly A Smith; Mary V Maliakal; Jason X-J Yuan
Journal:  Am J Physiol Cell Physiol       Date:  2011-10-26       Impact factor: 4.249

Review 5.  Current and future treatments of pulmonary arterial hypertension.

Authors:  Natascha Sommer; Hossein A Ghofrani; Oleg Pak; Sebastien Bonnet; Steve Provencher; Olivier Sitbon; Stephan Rosenkranz; Marius M Hoeper; David G Kiely
Journal:  Br J Pharmacol       Date:  2020-03-23       Impact factor: 8.739

6.  MicroRNA-138 and MicroRNA-25 Down-regulate Mitochondrial Calcium Uniporter, Causing the Pulmonary Arterial Hypertension Cancer Phenotype.

Authors:  Zhigang Hong; Kuang-Hueih Chen; Asish DasGupta; Francois Potus; Kimberly Dunham-Snary; Sebastien Bonnet; Lian Tian; Jennifer Fu; Sandra Breuils-Bonnet; Steeve Provencher; Danchen Wu; Jeffrey Mewburn; Mark L Ormiston; Stephen L Archer
Journal:  Am J Respir Crit Care Med       Date:  2017-02-15       Impact factor: 21.405

7.  Orai1 Inhibitors as Potential Treatments for Pulmonary Arterial Hypertension.

Authors:  Bastien Masson; Hélène Le Ribeuz; Jessica Sabourin; Loann Laubry; Emily Woodhouse; Richard Foster; Yann Ruchon; Mary Dutheil; Angèle Boët; Maria-Rosa Ghigna; Vincent Thomas De Montpreville; Olaf Mercier; David J Beech; Jean-Pierre Benitah; Marc A Bailey; Marc Humbert; David Montani; Véronique Capuano; Fabrice Antigny
Journal:  Circ Res       Date:  2022-09-27       Impact factor: 23.213

8.  17β-Estradiol via Orai1 activates calcium mobilization to induce cell proliferation in epithelial ovarian cancer.

Authors:  Xiaoyu Lv; Chunlei Miao; Mengyan Liu; Xinbo Wang; Lin Wang; Di Wang
Journal:  J Biochem Mol Toxicol       Date:  2020-08-25       Impact factor: 3.642

9.  Resistin-like molecule β acts as a mitogenic factor in hypoxic pulmonary hypertension via the Ca2+-dependent PI3K/Akt/mTOR and PKC/MAPK signaling pathways.

Authors:  Heshen Tian; Lei Liu; Ying Wu; Ruiwen Wang; Yongliang Jiang; Ruicheng Hu; Liming Zhu; Linwei Li; Yanyan Fang; Chulan Yang; Lianzhi Ji; Guoyu Liu; Aiguo Dai
Journal:  Respir Res       Date:  2021-01-06

Review 10.  ORAI Channels as Potential Therapeutic Targets in Pulmonary Hypertension.

Authors:  Baptiste Rode; Marc A Bailey; Roger Marthan; David J Beech; Christelle Guibert
Journal:  Physiology (Bethesda)       Date:  2018-07-01
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